DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7024 and pdha1

DIOPT Version :9

Sequence 1:	NP_572182.1	Gene:	CG7024 / 31407	FlyBaseID:	FBgn0029722	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_012812481.1	Gene:	pdha1 / 549826	XenbaseID:	XB-GENE-952669	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	192/349 - (55%)
Similarity:	240/349 - (68%)	Gaps:	6/349 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ENTF---KC--YDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQ 99
            |.||   ||  :.||.||.....|:||..|..|..|..:||.|..:...||::.||||||||:||
Frog    43 EATFDIKKCDVHRLEEGPPTQAVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQ 107

  Fly   100 EAVAVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGCSRGKGGSMHMYSDKFYG 164
            ||..||::..:...|.:|||||.|.::|..|||:.||:|||.|.|.||::|||||||||:..|||
Frog   108 EACCVGLEAAINPTDHLITAYRAHGYSYTRGVSVKEILAELTGRRGGCAKGKGGSMHMYAKNFYG 172

  Fly   165 GNGIVGAQVPLGAGIGLAHSYRKDNGVSVVLYGDGAANQGQIFESFNMAKLWCLPCIFVCENNHY 229
            |||||||||||||||.||..:...:.:.|.||||||||||||||::|||.||.|||||:||||.|
Frog   173 GNGIVGAQVPLGAGIALACKFFGKDEICVALYGDGAANQGQIFETYNMAALWKLPCIFICENNRY 237

  Fly   230 GMGTHVKRASAMTEFYMRGQYIPGLWVDGNQVLAVRSATQFAVDHALK-HGPIVLEMSTYRYVGH 293
            ||||.|:||:|.|::|.||.|||||.|||..||.||.|||||.||... .|||::|:.||||.||
Frog   238 GMGTSVERAAASTDYYKRGDYIPGLRVDGMDVLCVREATQFAADHCRSGKGPILMELQTYRYHGH 302

  Fly   294 SMSDPGTSYRSREEVQSTREKRDPITSFRSQIIALCLADEEELKALDDKTRKQVDSICKKATTDR 358
            ||||||.|||:|||:|..|.|.||||..:.:::...|:..||||.:|.:.||:::...:.||||.
Frog   303 SMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLSSVEELKEIDVEVRKEIEEAAQFATTDP 367

  Fly   359 EVELDELHTDIYAKNVDGKIRGVS 382
            |..|:|:...||.......:||.:
Frog   368 EPPLEEIANHIYNNEPTFDVRGAN 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7024	NP_572182.1	TPP_enzymes	37..381	CDD:294952	191/346 (55%)
pdha1	XP_012812481.1	PDH_E1_alph_y	68..379	CDD:274473	178/310 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318981at33208
OrthoFinder	1	1.000	-	-		FOG0001471
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X926
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010