DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7024 and pdha1b

DIOPT Version :9

Sequence 1:	NP_572182.1	Gene:	CG7024 / 31407	FlyBaseID:	FBgn0029722	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_005162743.1	Gene:	pdha1b / 436672	ZFINID:	ZDB-GENE-040718-96	Length:	400	Species:	Danio rerio

Alignment Length:	377	Identity:	197/377 - (52%)
Similarity:	260/377 - (68%)	Gaps:	8/377 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RCSGAHSILERNMLCRIIGRHKCSCLTLENTF---KC--YDLENGPTMDVELSREDALTMYTQML 71
            :.:||.::.|.:.:  ::.....:..|.:..|   :|  :.|:.||::...|:|||.|..|..|.
Zfish    17 KVNGAQTVSEGSRV--VVSSRSFADFTPQANFDIKRCDLHRLDEGPSVQTVLTREDGLKYYRMMQ 79

  Fly    72 ELRRFETVAGNYYKERKIRGFCHLYNGQEAVAVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEI 136
            .:||.|..|...||::.||||||||:||||.|||::..::..|.:|||||.|.:||..|||:.||
Zfish    80 TMRRMELKADQLYKQKIIRGFCHLYDGQEACAVGIEAGIKPTDHLITAYRAHGYTYTRGVSVKEI 144

  Fly   137 MAELFGVRTGCSRGKGGSMHMYSDKFYGGNGIVGAQVPLGAGIGLAHSYRKDNGVSVVLYGDGAA 201
            ||||.|.|.|.::|||||||||:..|||||||||||||||||:.||..|:..|.:.|.|||||||
Zfish   145 MAELTGRRGGVAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVALACQYQGKNEICVTLYGDGAA 209

  Fly   202 NQGQIFESFNMAKLWCLPCIFVCENNHYGMGTHVKRASAMTEFYMRGQYIPGLWVDGNQVLAVRS 266
            ||||||||||||.||.|||||:||||.|||||.|:||||.|::|.||.:||||.|||..||.||.
Zfish   210 NQGQIFESFNMAALWKLPCIFICENNKYGMGTSVERASASTDYYKRGDFIPGLRVDGMDVLGVRE 274

  Fly   267 ATQFAVDHALK-HGPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQIIALCL 330
            ||:||.|:... .|||::|:.||||.||||||||.|||:|||:|..|.|.||||:.:.::|:..:
Zfish   275 ATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPITTLKDRMISSNM 339

  Fly   331 ADEEELKALDDKTRKQVDSICKKATTDREVELDELHTDIYAKNVDGKIRGVS 382
            |..||:|.:|...||:|:...:.||||.|..|::|...|:..:...::||.:
Zfish   340 ASLEEIKDIDADIRKEVEEAAQFATTDPEPPLEDLCNHIFYNDAPLEVRGTN 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7024	NP_572182.1	TPP_enzymes	37..381	CDD:294952	193/349 (55%)
pdha1b	XP_005162743.1	PDH_E1_alph_y	68..379	CDD:274473	184/310 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576769
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54057
OrthoDB	1	1.010	-	-		D318981at33208
OrthoFinder	1	1.000	-	-		FOG0001471
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100754
Panther	1	1.100	-	-	O	PTHR11516
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X926
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.720