DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7024 and Pdha2

DIOPT Version :9

Sequence 1:	NP_572182.1	Gene:	CG7024 / 31407	FlyBaseID:	FBgn0029722	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_446446.1	Gene:	Pdha2 / 117098	RGDID:	620095	Length:	391	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	185/379 - (48%)
Similarity:	246/379 - (64%)	Gaps:	20/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RNMLCRIIG------------RHKCSCLTLENTFKC-------YDLENGPTMDVELSREDALTMY 67
            |.||..::.            |...|.|...|...|       |.||.||.....|:||:||..|
  Rat     2 RKMLATVLSQVFSGMVQKPALRGLLSSLKFSNDATCDIKKCDLYLLEQGPPTSTVLTREEALKYY 66

  Fly    68 TQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAVAVGMKQRLRSCDSVITAYRCHAWTYLMGVS 132
            ..|..:||.|..|...||::.|||||||.:||||..||::..:...|.:||:||.|...|..|:|
  Rat    67 RNMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACNVGLEAGINPTDHIITSYRAHGLCYTRGLS 131

  Fly   133 LYEIMAELFGVRTGCSRGKGGSMHMYSDKFYGGNGIVGAQVPLGAGIGLAHSYRKDNGVSVVLYG 197
            :..|:|||.|.:.||::|||||||||:..|||||||||||||||||:.||..|.|:..:.:.|||
  Rat   132 VKSILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVALACKYLKNGQICLALYG 196

  Fly   198 DGAANQGQIFESFNMAKLWCLPCIFVCENNHYGMGTHVKRASAMTEFYMRGQYIPGLWVDGNQVL 262
            ||||||||:||::||:.||.|||:|:||||.|||||.::|::|.|:::.:|..||||.|:|..:|
  Rat   197 DGAANQGQVFEAYNMSALWKLPCVFICENNRYGMGTAIERSAASTDYHKKGFVIPGLRVNGMDIL 261

  Fly   263 AVRSATQFAVDHALK-HGPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQII 326
            :||.||:||.||... .||||:|:.||||.||||||||.|||:|||||:.|.|.|||...|.::|
  Rat   262 SVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRTREEVQNVRSKSDPIMLLRERMI 326

  Fly   327 ALCLADEEELKALDDKTRKQVDSICKKATTDREVELDELHTDIYAKNVDGKIRG 380
            :..|:..||||.:|...:|:|:...:.||||.|..|::|...:|.:|...::||
  Rat   327 SNNLSSVEELKEIDADVKKEVEEAAQFATTDPEPPLEDLANYLYHQNPPFEVRG 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7024	NP_572182.1	TPP_enzymes	37..381	CDD:294952	180/352 (51%)
Pdha2	NP_446446.1	PDH_E1_alph_y	59..371	CDD:274473	167/311 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54057
OrthoDB	1	1.010	-	-		D318981at33208
OrthoFinder	1	1.000	-	-		FOG0001471
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100754
Panther	1	1.100	-	-	O	PTHR11516
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X926
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860