Protein Alignment Pdha and PRS4

DIOPT Version :9

• Sequence 1: NP_726945.1
• Gene: Pdha / 31406
• FlyBaseID: FBgn0028325
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_009485.3
• Gene: PRS4 / 852211
• SGDID: S000000164
• Length: 326
• Species: Saccharomyces cerevisiae
• Alignment Length: 436
• Identity: 79/436 - (18%)
• Similarity: 134/436 - (30%)
• Gaps: 170/436 - (38%)

  Fly    12 PIIVKQLQKRCHNNNNNNIIISGCRILSNNNNNSSIDIIRNGRYSSSFFGLFQNAAQAGV--SKT 74
            |.:.:|:.|:.      .|.:|...:...:|..:|:.|..:.|....:.      .|.|:  .:.
Yeast    23 PDLAEQISKKL------GIPLSKVGVYQYSNKETSVTIGESLRDEDVYI------IQTGIGEQEI 75

  Fly    75 NNYATE----------------ATVQVNRPFKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLE 123
            |::..|                .||..|.|:.  |.|:         ||::....|.......|:
Yeast    76 NDFLMELLILIHACKIASARKITTVIPNFPYA--RQDK---------KDKSRAPITAKLVANLLQ 129

  Fly   124 TAAG------NLYKEKIIRGFCH-----LYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGV 177
            ||..      :|:..: |:||.|     ||:  |...:.......|.||.|.            |
Yeast   130 TAGADHVITMDLHASQ-IQGFFHIPVDNLYA--EPSVLNYIRTKTDFDNAIL------------V 179

  Fly   178 SPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALY 242
            ||..                ||:..:.|         :..::.|...:....:.|.|....:.|.
Yeast   180 SPDA----------------GGAKRVAA---------LADKLDLNFALIHKERQKANEVSKMVLV 219

  Fly   243 GDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDV 307
            ||          ..|.:.|....:...|                            |..|...|.
Yeast   220 GD----------VTNKSCLLVDDMADTC----------------------------GTLVKACDT 246

  Fly   308 LAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCI 372
            |....|.|  :..:.|||         .:||.:          ||:::..|..|
Yeast   247 LMEHGAKE--VIAIVTHG---------IFSGSA----------REKLRNSRLSR----------- 279

  Fly   373 ELGLITTDEVKA-IDLKVRKEVDEATAFAKSDAEL----GVSHLWT 413
               ::.|:.|.. :||.:..::|.:..||::...|    .||:|:|
Yeast   280 ---IVCTNTVPVDLDLPIADQIDISPTFAEAIRRLHNGESVSYLFT 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdha	NP_726945.1	TPP_enzymes	78..426	CDD:294952	67/368 (18%)
PRS4	NP_009485.3	PrsA	11..322	CDD:223538	78/434 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900