Protein Alignment Pdha and pdha1

DIOPT Version :9

• Sequence 1: NP_726945.1
• Gene: Pdha / 31406
• FlyBaseID: FBgn0028325
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: XP_012812481.1
• Gene: pdha1 / 549826
• XenbaseID: XB-GENE-952669
• Length: 400
• Species: Xenopus tropicalis
• Alignment Length: 369
• Identity: 218/369 - (59%)
• Similarity: 276/369 - (74%)
• Gaps: 4/369 - (1%)

  Fly    61 GLFQNAAQAGVSKTN--NYATEATVQVNRPFKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLE 123
            |....|.:..|:..|  ::|:|||..:.: ..:|||:|||.|:..||::|.|:||..||||||:|
 Frog    22 GAANEAVRVMVASRNYADFASEATFDIKK-CDVHRLEEGPPTQAVLTREQGLQYYRTMQTIRRME 85

  Fly   124 TAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTG 188
            ..:..|||:||||||||||.|||||.||::||:...|::|:|||.||::|..|||...:||||||
 Frog    86 LKSDQLYKQKIIRGFCHLYDGQEACCVGLEAAINPTDHLITAYRAHGYSYTRGVSVKEILAELTG 150

  Fly   189 VQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVF 253
            .:||||:||||||||||.||||||||||||||||||:.||||:.|...:|:||||||||||||:|
 Frog   151 RRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKFFGKDEICVALYGDGAANQGQIF 215

  Fly   254 EAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAI 318
            |.||||.|||||.||:||||.||||||.|||:.:||||.|||.:||:.|||||||.||.||:||.
 Frog   216 ETYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDYIPGLRVDGMDVLCVREATQFAA 280

  Fly   319 NYVNT-HGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEV 382
            ::..: .||::||..||||.||||||||.||||||||||||.|.||||..|:..:...|.:.:|:
 Frog   281 DHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLSSVEEL 345

  Fly   383 KAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKLRG 426
            |.||::||||::||..||.:|.|..:..:...:|:|.....:||
 Frog   346 KEIDVEVRKEIEEAAQFATTDPEPPLEEIANHIYNNEPTFDVRG 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdha	NP_726945.1	TPP_enzymes	78..426	CDD:294952	212/348 (61%)
pdha1	XP_012812481.1	PDH_E1_alph_y	68..379	CDD:274473	197/310 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	408	1.000	Domainoid score	I691
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	449	1.000	Inparanoid score	I1586
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318981at33208
OrthoFinder	1	1.000	-	-		FOG0001471
OrthoInspector	1	1.000	-	-		oto103879
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2211
SonicParanoid	1	1.000	-	-		X926
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090