Protein Alignment Pdha and CG8199

DIOPT Version :9

• Sequence 1: NP_726945.1
• Gene: Pdha / 31406
• FlyBaseID: FBgn0028325
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_649905.1
• Gene: CG8199 / 41149
• FlyBaseID: FBgn0037709
• Length: 439
• Species: Drosophila melanogaster
• Alignment Length: 416
• Identity: 114/416 - (27%)
• Similarity: 167/416 - (40%)
• Gaps: 70/416 - (16%)

  Fly    57 SSFFGLFQNAAQAGVSKTN-----NYATEATVQVNRPFKLHRLDEGPATEVKLTKDQAL------ 110
            |..:..|..|....|||.|     :||         |..::|:.:........|:|..|
  Fly    40 SEDYANFPGAKAPFVSKLNLIQPEDYA---------PIPIYRVMDQDGYIADETQDPQLGREVVE 95

  Fly   111 KYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYS---GQEACAVGMKAAMRDVDNIISAYRVHGWT 172
            |.:..|..:..::..   || |...:|....|.   |:||..:|..||:...|.|...||..|..
  Fly    96 KMFRDMVLLNTMDKI---LY-ESQRQGRISFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVL 156

  Fly   173 YLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP---NFYGGNGIVGAQVPLGAGVGLACKYKGN 234
            ...|......:.:..|......|||...:| |..   ||...:..:..|:|...|...|.|.:.|
  Fly   157 VWRGFRIDQFIDQCYGNTDDLGRGKQMPVH-YGSRELNFVTISSPLSTQMPQAVGAAYAMKLRPN 220

  Fly   235 GGMCLALY-GDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALP 298
            ...|:..| |:|||::|....|:|.|.....|.|..|.||.:.:.|.|.      :.| :||.:.
  Fly   221 NDACVVCYFGEGAASEGDAHAAFNFAATLGCPAILFCRNNGFAISTPSH------EQY-KGDGIA 278

  Fly   299 G----------IWVDGMDVLAVRSATEFAINYV-NTHGPLVMETNTYRYSGHSMSDPGTSYRTRE 352
            |          |.|||.||.||.:|.:.|..|| ..:.|:|.|...||...||.||..|:||..|
  Fly   279 GRGPMGYGITTIRVDGTDVFAVYNAMKAAREYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAE 343

  Fly   353 EIQEVRQKRDPITSFKELCIELG----LITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWT 413
            ||:.......||:..|...:..|    .:..:.||.|..||.|::      |.|:.:|..:  |.
  Fly   344 EIEIWNSVEHPISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQI------AVSEKKLKPN--WR 400

  Fly   414 DVYSNNLEPKLRGTIAYDIDHIQERK 439
            :::        .|..|...||:.|::
  Fly   401 EMF--------EGVYAEMPDHLIEQR 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdha	NP_726945.1	TPP_enzymes	78..426	CDD:294952	101/375 (27%)
CG8199	NP_649905.1	TPP_E1_PDC_ADC_BCADC	97..389	CDD:238958	90/309 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444244
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840