DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pp2C1 and PPM1F

DIOPT Version :9

Sequence 1:NP_001284867.1 Gene:Pp2C1 / 31404 FlyBaseID:FBgn0022768 Length:1427 Species:Drosophila melanogaster
Sequence 2:NP_055449.1 Gene:PPM1F / 9647 HGNCID:19388 Length:454 Species:Homo sapiens


Alignment Length:348 Identity:89/348 - (25%)
Similarity:140/348 - (40%) Gaps:70/348 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 RKYMEDQ------FSVAYQES-PITHELEYAFFGIYDGHGGPEAALFAKEHLMLEIVKQKQFWSD 324
            |:.|||:      |:..:..| |:..    |:|.::|||||.:||.:|..|:.....:|.:..:|
Human   166 RRKMEDRHVSLPSFNQLFGLSDPVNR----AYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTD 226

  Fly   325 QDEDVLRAIREGYIATHFAMWREQEKWPRTANGHLSTAGTTATVAFMRREKIYIGHVGDSGIVLG 389
            .:    .|:||       |..|..:.:.|.|......:|||...|.:....:::..:|||.::|.
Human   227 PE----GALRE-------AFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILV 280

  Fly   390 YQNKGERNWRARPLTTDHKPESLAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMHRGPIRRRTLV 454
            .|.:..:      |...|:||...||.||:..||.|:                 |....|.... 
Human   281 QQGQVVK------LMEPHRPERQDEKARIEALGGFVS-----------------HMDCWRVNGT- 321

  Fly   455 DEIPFLAVARSLGDLWSYNSRFKEFVVSPDPDVKVVKINPSTFRCLIFGTDGLWNVVTAQEAVDS 519
                 |||:|::||:      |::..||.:.|.....:..|. ..|:...||.::||..||.|..
Human   322 -----LAVSRAIGDV------FQKPYVSGEADAASRALTGSE-DYLLLACDGFFDVVPHQEVVGL 374

  Fly   520 VRKEHLIGEILNEQDVMNPSKALVDQALKTWAAKKMRADNTSVVTVIL-TPAARNNSPTTPTRSP 583
            | :.||..:        ..|...|.:.|...|.::...||.:|:.|.| .|.............|
Human   375 V-QSHLTRQ--------QGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGGNQGEGDP 430

  Fly   584 SAMARDNDLEVELLLEEDDEELP 606
            .|..|..||...  |.|.:.:.|
Human   431 QAEGRRQDLPSS--LPEPETQAP 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pp2C1NP_001284867.1 PP2Cc 256..567 CDD:238083 79/306 (26%)
PPM1FNP_055449.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..28
PP2C 155..406 CDD:278884 76/299 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 419..454 8/35 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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