DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pp2C1 and Pptc7

DIOPT Version :9

Sequence 1:	NP_001284867.1	Gene:	Pp2C1 / 31404	FlyBaseID:	FBgn0022768	Length:	1427	Species:	Drosophila melanogaster
Sequence 2:	NP_796216.2	Gene:	Pptc7 / 320717	MGIID:	2444593	Length:	310	Species:	Mus musculus

Alignment Length:	307	Identity:	63/307 - (20%)
Similarity:	99/307 - (32%)	Gaps:	100/307 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1102 AIVAYGD--STETVGGTAGASGTPAAGRVGGGGGGGGG------------------------RGS 1140
            ::::||.  :...:||.:...     .|.|||||||||                        :|:
Mouse     3 SVLSYGRLVARAVLGGLSQTD-----PRAGGGGGGGGGSSGDYGLVTAGCGFGKDFRKGLLKKGA 62

  Fly  1141 ASGGSSPAVAANSRRSVNVVANASGNSASK---VVPSSSSMMMTRRSHTLTASG--------GVN 1194
            ..|..:..||.:  ||.:|:..|.|....:   |.||..|..:.|....|...|        |:
Mouse    63 CYGDDACFVARH--RSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGI- 124

  Fly  1195 KRQLRSSLCTLGLG----VGVGVGLGMDLDMTKRTLRTRNVP-----ALSGGSATPSSN------ 1244
               |.:|.|.|...    :|......:.||.:...|.|.|:.     .:.||.....|:
Mouse   125 ---LTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYF 186

  Fly  1245 --------SSPASGG----SSP-----AGFTSPASPVITSRGSG------SRTTASPARRLKRSH 1286
                    :.|.:.|    .||     ..|......:|.:...|      ........::||.|:
Mouse   187 NTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSN 251

  Fly  1287 EDREQRMSLR--------------RSTLSGSASGSGLVGTGGSPSNV 1319
            .:..||.:..              .|..:..|..:||...||.|.::
Mouse   252 YESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp2C1	NP_001284867.1	PP2Cc	256..567	CDD:238083
Pptc7	NP_796216.2	PP2Cc	66..302	CDD:381813	47/239 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900