DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pp2C1 and Ppm1f

DIOPT Version :9

Sequence 1:	NP_001284867.1	Gene:	Pp2C1 / 31404	FlyBaseID:	FBgn0022768	Length:	1427	Species:	Drosophila melanogaster
Sequence 2:	NP_786931.1	Gene:	Ppm1f / 287931	RGDID:	631363	Length:	450	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	108/495 - (21%)
Similarity:	183/495 - (36%)	Gaps:	108/495 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 SSSGNNNNNSACHPALDASSDVVVVE-PAAVGVAQEEEEEPEQRPERISIPIPDLAFTEMEAYAE 156
            |.:..|::..||...:....|.::.: ||.:.:         :.|....:|...|...|:||...
  Rat     3 SGAPQNSSQMACDGEIPGFLDTLLQDFPAPLSL---------ESPLPWKVPGTVLGQEEVEAELT 58

  Fly   157 DIVVDMEGGSPAKPLNPKKQRLNSATTTTINRSRGGGAAQSRLRRSAAIVPPRSIPESCASSSNS 221
            ::.:...|...|.|          |....:.........|:.|...      :.:||    ....
  Rat    59 ELAMGFLGSRNAPP----------AVAAAVTHEAISQLLQTDLSEF------KRLPE----QEEE 103

  Fly   222 NSSSSSNSNSSSSSATGSSASTGNP--SPCSSLGVNMRVTGQCCQ-----------GGRKYMEDQ 273
            .........::...|.|.|.|..|.  ..||.....:.:|.|..|           ..|:.|||:
  Rat   104 EEEEEERVLTTLLDAKGLSRSFFNCLWEVCSQWQKRVPLTAQAPQRKWLVSIHAIRNTRRKMEDR 168

  Fly   274 ------FSVAYQESPITHELEYAFFGIYDGHGGPEAALFAKEHLMLEIVKQKQFWSDQDEDVLRA 332
                  |:..:..|...|.   |:|.::|||||.:||.:|..|:......|.:..:|.    ..|
  Rat   169 HVSLPAFNHLFGLSDSVHR---AYFAVFDGHGGVDAARYASVHVHTNASHQPELLTDP----AAA 226

  Fly   333 IREGYIATHFAMWREQEKWPRTANGHLSTAGTTATVAFMRREKIYIGHVGDSGIVLGYQNKGERN 397
            ::|.:..|. .|:.::.|..|.      .:|||...|.:....:::..:|||.::|..|.:..:
  Rat   227 LKEAFRHTD-QMFLQKAKRERL------QSGTTGVCALITGAALHVAWLGDSQVILVQQGQVVK- 283

  Fly   398 WRARPLTTDHKPESLAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMHRGPIRRRTLVDEIPFLAV 462
                 |...||||...||:||:..||.|::..     .|.                |:..  |||
  Rat   284 -----LMEPHKPERQDEKSRIEALGGFVSLMD-----CWR----------------VNGT--LAV 320

  Fly   463 ARSLGDLWSYNSRFKEFVVSPDPDVKVVKINPSTFRCLIFGTDGLWNVVTAQEAVDSVRKEHLIG 527
            :|::||:      |::..||.:.|....::. .....|:...||.::||...|....|.     |
  Rat   321 SRAIGDV------FQKPYVSGEADAASRELT-GLEDYLLLACDGFFDVVPHHEIPGLVH-----G 373

  Fly   528 EILNEQDVMNPSKALVDQALKTWAAKKMRADNTSVVTVIL 567
            .:|.::.    |...|.:.|...|..:...||.:|:.|.|
  Rat   374 HLLRQKG----SGMHVAEELVAVARDRGSHDNITVMVVFL 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp2C1	NP_001284867.1	PP2Cc	256..567	CDD:238083	79/327 (24%)
Ppm1f	NP_786931.1	PP2C	151..402	CDD:395385	73/309 (24%)
Ppm1f	NP_786931.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	420..450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900