Protein Alignment Pp2C1 and PPM1K

DIOPT Version :9

• Sequence 1: NP_001284867.1
• Gene: Pp2C1 / 31404
• FlyBaseID: FBgn0022768
• Length: 1427
• Species: Drosophila melanogaster
• Sequence 2: NP_689755.3
• Gene: PPM1K / 152926
• HGNCID: 25415
• Length: 372
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 117/414 - (28%)
• Similarity: 178/414 - (42%)
• Gaps: 96/414 - (23%)

  Fly   178 LNSATTTTINRSRGGGAAQSRLRRSAAIVPPRSIPESCASSSNSNSSSSSNSNSSSSSATGS--- 239
            :::|...|:.||.|....:..|..|..:...|.:..:|.||::....|..:.:.|.|.||..
Human     1 MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPATWDNFG 65

  Fly   240 --------------SASTGNPSPCSSLGVNMRVTGQCCQGGRKYMEDQFSVAYQESPITHELEYA 290
                          |...|.|.|..|| .|:....|.  |.||..||:|..|    .:|.|:.|
Human    66 IWDNRIDEPILLPPSIKYGKPIPKISL-ENVGCASQI--GKRKENEDRFDFA----QLTDEVLY- 122

  Fly   291 FFGIYDGHGGPEAALFAKEHL---MLEIV-KQKQFWSDQDEDVLR----AIREGYIATHFAMWRE 347
             |.:|||||||.||.|...|:   ::::: |:|..     |.:|.    .|.:.: ::|..:
Human   123 -FAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNL-----ETLLTLAFLEIDKAF-SSHARL--- 177

  Fly   348 QEKWPRTANGHLSTAGTTATVAFMRRE-KIYIGHVGDSGIVLGYQNKGERNWRARPLTTDHKPES 411
                  :|:..|.|:|||||||.:|.. ::.:..||||..:|.      |..:...||.||.||.
Human   178 ------SADATLLTSGTTATVALLRDGIELVVASVGDSRAILC------RKGKPMKLTIDHTPER 230

  Fly   412 LAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMHRGPIRRRTLVDEIPFLAVARSLGDLWSYNSRF 476
            ..||.||::.||.||         ||....|...|.            ||:.||:|||     ..
Human   231 KDEKERIKKCGGFVA---------WNSLGQPHVNGR------------LAMTRSIGDL-----DL 269

  Fly   477 KEFVVSPDPDVKVVKINPSTFRCLIFGTDGLWNVVTAQEAVDSVRKEHLIGEILNEQDVMNPSKA 541
            |...|..:|:.|.:|::.:....|:..|||:..:|.:||..|.|.:.|         |....:.|
Human   270 KTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCH---------DPNEAAHA 325

  Fly   542 LVDQALKTWAAKKMRADNTSVVTV 565
            :.:||::...     .||::.|.|
Human   326 VTEQAIQYGT-----EDNSTAVVV 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2C1	NP_001284867.1	PP2Cc	256..567	CDD:238083	94/319 (29%)
PPM1K	NP_689755.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..55		4/20 (20%)
		PP2Cc	95..346	CDD:238083	94/319 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810