Protein Alignment Pp2C1 and PPM1L

DIOPT Version :10

• Sequence 1: NP_525074.2
• Gene: Pp2C1 / 31404
• FlyBaseID: FBgn0022768
• Length: 1427
• Species: Drosophila melanogaster
• Sequence 2: NP_640338.2
• Gene: PPM1L / 151742
• HGNCID: 16381
• Length: 360
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 104/330 - (31%)
• Similarity: 154/330 - (46%)
• Gaps: 69/330 - (20%)

  Fly   255 NMRVTGQCCQGGRKYMEDQFSVAYQESPITHELEYAFFGIYDGHGGPEAALFAKEHLMLEIVKQ- 318
            |..|.....||.|.:|||:|.|....:..||.   :.|||:|||||..||.:.|..|. |.:||
Human    90 NHNVAVYSIQGRRDHMEDRFEVLTDLANKTHP---SIFGIFDGHGGETAAEYVKSRLP-EALKQH 150

  Fly   319 -KQFWSDQDEDVL--RAIREGYIATHFAMWREQ-EKWPRTANGHLSTAGTTATVAFMRREKIYIG 379
             :.:..|::..||  :.|.|..|   .::.||. ||    .......||||..:|.:..:.:.:.
Human   151 LQDYEKDKENSVLSYQTILEQQI---LSIDREMLEK----LTVSYDEAGTTCLIALLSDKDLTVA 208

  Fly   380 HVGDSGIVLGYQNKGERNWRARPLTTDHKPESLAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMH 444
            :||||..||     .:::..|.||:.||||..|.|:.||:|:||.::. :|..||
Human   209 NVGDSRGVL-----CDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISF-NGSWRV---------- 257

  Fly   445 RGPIRRRTLVDEIPFLAVARSLGD--LWSYNSRFKEFVVSPDPDVKVVKINPSTFRCLIFGTDGL 507
            :|            .||::|||||  |.:.|      ||.||||:....::......:|..:|||
Human   258 QG------------ILAMSRSLGDYPLKNLN------VVIPDPDILTFDLDKLQPEFMILASDGL 304

  Fly   508 WNVVTAQEAVDSVRKEHLIGEILNEQDVMNPSKALVDQALKTWAAKKMRADNTSVVTVILTPAAR 572
            |:..:.:|||      ..|.|.|:|...  .:|::|.|:.....     .||.:|:.|    ..|
Human   305 WDAFSNEEAV------RFIKERLDEPHF--GAKSIVLQSFYRGC-----PDNITVMVV----KFR 352

  Fly   573 NNSPT 577
            |:|.|
Human   353 NSSKT 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2C1	NP_525074.2	PP2Cc	256..567	CDD:238083	99/317 (31%)
PPM1L	NP_640338.2	PP2Cc	93..351	CDD:238083	99/319 (31%)