DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3009 and pla2g3

DIOPT Version :9

Sequence 1:	NP_001162665.1	Gene:	CG3009 / 31402	FlyBaseID:	FBgn0029720	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001032489.1	Gene:	pla2g3 / 641423	ZFINID:	ZDB-GENE-051113-96	Length:	528	Species:	Danio rerio

Alignment Length:	287	Identity:	86/287 - (29%)
Similarity:	120/287 - (41%)	Gaps:	63/287 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ISDMTMSVMVELSSRHPFCKMHTDRGDIQRMLLQSDPRRIRQVPRE---------SVMELE---- 83
            |:|..||..:|.||   |.::..:|.||..:.....|..:..|..|         .:|.:|
Zfish    77 ITDSYMSRCLEDSS---FSELLDERFDISVLTEADGPCEVAGVTEEFAASVRRARDLMSVEPDGF 138

  Fly    84 -EVCRRQGSYGHEFRGGLGFIYPGTKWCGPGTAATSYDDLGAHAREDRCCREHDMCPDVLNVGEC 147
             |......|.....|....::.|||.|||.|..||.:.|||.....|:||||||.|...:.....
Zfish   139 VEQDSDVSSIKTLQRSKRAWMIPGTLWCGSGNKATGWTDLGVFEETDKCCREHDHCKHTIPSFSY 203

  Fly   148 RRGLCNRGTFTRSHCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCFQ--ERSPC-------- 202
            ..|:.|...||.||||||.||||||...|...:|.:|..|:||::::||:  :|:.|
Zfish   204 DHGVFNTNLFTLSHCDCDNRFRRCLLGVNNSMSNLVGYGFFNVLKMSCFKFSQRTQCAKRTWWGR 268

  Fly   203 ------SAHQRFEDFYYRTDHCPAE--------FRQADLYVPPHGDNLIAK------ILAHPQGR 247
                  :.:...:|....||..|.:        |:||...    |.|.:.|      |:.....|
Zfish   269 CVMSELAQYAVVKDAANYTDTLPEQEMESLETSFQQAITI----GQNQVTKNMEESLIIQSKDSR 329

  Fly   248 ----ALA------APSWT--IPAKSTA 262
                ||:      .||.|  :|.||.|
Zfish   330 NGTEALSPVSTSPGPSVTTLLPRKSEA 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3009	NP_001162665.1	PLA2_bee_venom_like	102..198	CDD:153093	44/97 (45%)
pla2g3	NP_001032489.1	PLA2_bee_venom_like	158..254	CDD:153093	44/95 (46%)
pla2g3	NP_001032489.1	PLA2_like	<374..450	CDD:297013
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6656
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003412
OrthoInspector	1	1.000	-	-		otm25517
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12253
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5827
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	8.000