DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3009 and Pla2g3

DIOPT Version :9

Sequence 1:	NP_001162665.1	Gene:	CG3009 / 31402	FlyBaseID:	FBgn0029720	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_766379.2	Gene:	Pla2g3 / 237625	MGIID:	2444945	Length:	504	Species:	Mus musculus

Alignment Length:	253	Identity:	73/253 - (28%)
Similarity:	108/253 - (42%)	Gaps:	64/253 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 RHPFCKMHTDRGDIQRML--LQSD-------------PRRIRQVPRESVMELEEVCRRQGSYGHE 95
            :|.|  :.|....:||.|  |||.             .|..|.:.:....:.|...||:
Mouse    89 QHSF--IQTPGPALQRALATLQSQWEACQRSQDSPTGAREKRAIEQSGAPDREHRRRRR------ 145

  Fly    96 FRGGLGFIYPGTKWCGPGTAATSYDDLGAHAREDRCCREHDMCPDVLNVGECRRGLCNRGTFTRS 160
                 |:..|||.|||.|.:|.:..:||.....|.||||||.||..::..:...|:.|....|.|
Mouse   146 -----GWTIPGTLWCGVGNSAENASELGVFHGPDLCCREHDQCPQTISPLQYNYGIRNFRFHTIS 205

  Fly   161 HCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCF--QERSPC----------------SAHQR 207
            ||||||||::||::.....::.:|..|:||:::.||  :|:..|                .||.|
Mouse   206 HCDCDARFQQCLRSQGDSISDIMGVAFFNVLEIPCFVLKEQEACVAWNWWGGCRAYGSTPLAHLR 270

  Fly   208 FEDFYYRTDHCPAEFR-QADLYVPPHGDNLIAKILAHPQGRALAAPSWTIPAKSTARR 264
            ...:|      .|.:: :|..|.|.......:|   |||.|.        |.::.|||
Mouse   271 PRTYY------NASWKAEATSYTPSPQSPAPSK---HPQKRG--------PQQTQARR 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3009	NP_001162665.1	PLA2_bee_venom_like	102..198	CDD:153093	39/97 (40%)
Pla2g3	NP_766379.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	115..143		3/27 (11%)
		Phospholipase A2-like. /evidence=ECO:0000250\|UniProtKB:Q9NZ20	146..287		48/146 (33%)
		PLA2_bee_venom_like	147..243	CDD:153093	39/95 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..350		11/38 (29%)
		PLA2_group_III_like	295..422	CDD:153094	9/28 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7417
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8069
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003412
OrthoInspector	1	1.000	-	-		otm42980
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12253
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5827
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.950