Protein Alignment Torsin and TOR3A

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_071766.2
• Gene: TOR3A / 64222
• HGNCID: 11997
• Length: 397
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 91/299 - (30%)
• Similarity: 157/299 - (52%)
• Gaps: 21/299 - (7%)

  Fly    47 YCRFAECC--DDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQ 109
            ||.|.:||  .|..|......||..|...|.|||:|:|.::..::.::.: .:..|.|.:||||.
Human   105 YCSFKDCCPRGDCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLET-PQPEKALALSFHGW 168

  Fly   110 PGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFI 174
            .||||||||..:.:.:|..|..|:.|..::....||....|..|:.::.:.:|:|.:.|.::|||
Human   169 SGTGKNFVARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQQLCHQTLFI 233

  Fly   175 FDEVDKMPSGVFDQLTSLVDYNAFVDG--TDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDT 237
            |||.:|:..|:.:.|...::..| .:|  .::...||:||||..|..|...:..::|.|..||:.
Human   234 FDEAEKLHPGLLEVLGPHLERRA-PEGHRAESPWTIFLFLSNLRGDIINEVVLKLLKAGWSREEI 297

  Fly   238 RLSDFEPLLR-KAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKC-----LEAELLRWRRD 296
            .:...||.|: :....:|.|...:.:::.::||:||||||:|..||..|     |..|||
Human   298 TMEHLEPHLQAEIVETIDNGFGHSRLVKENLIDYFIPFLPLEYRHVRLCARDAFLSQELL----- 357

  Fly   297 PKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKV 335
                ..::.:::|....:...:...||:..|||::.:::
Human   358 ----YKEETLDEIAQMMVYVPKEEQLFSSQGCKSISQRI 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	42/128 (33%)
		AAA	100..224	CDD:214640	44/125 (35%)
TOR3A	NP_071766.2	Torsin	106..234	CDD:148114	42/128 (33%)
		AAA	165..280	CDD:214640	40/115 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147051
Domainoid	1	1.000	106	1.000	Domainoid score	I6568
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3713
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1453168at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40398
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.860