Protein Alignment Torsin and tor3a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001025592.2
• Gene: tor3a / 594980
• XenbaseID: XB-GENE-1005206
• Length: 389
• Species: Xenopus tropicalis
• Alignment Length: 322
• Identity: 102/322 - (31%)
• Similarity: 154/322 - (47%)
• Gaps: 30/322 - (9%)

  Fly    21 PLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIV 85
            |..|.||:.:       |..::...|  ..|...||| |...:..|...|.|.|.|||:....|:
 Frog    88 PTGSWDPMQM-------LSDWYARVT--DHAGLLDDR-ITNNLTGLRWDLGRRLHGQHVAEGLIL 142

  Fly    86 PALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEV 150
            ..|:..:..| :..|||.:||||..|||||..|..||:.:||...||..:..::.|..||..|.|
 Frog   143 TYLERFLQHG-EPLKPLALSFHGWTGTGKNLAARIIAENLYLDSQRSRCIRVFIPQLHFPHLSHV 206

  Fly   151 SNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNT 215
            ..|:|::.|.:|:....||:.||:|||.||:|.|:...:...:....    ...:.:||:||| :
 Frog   207 EAYKVQLENQIREVSSRCPQPLFVFDEADKIPKGLLSSIRLFLSSGK----QSQSHSIFLFLS-S 266

  Fly   216 AGSHIASHLG-SVMKNGRLREDTRLSDFEPLLRKAAYNMDGGMKKT-TMIESHVIDHFIPFLPME 278
            .||:..:.|. |....||.|::....|.|..||.|.....|.:..| .::|..:||..:||||:|
 Frog   267 MGSNAINELALSFWAAGRQRKEITADDLERPLRAAIKENQGDIPLTQQLMEEGLIDGLVPFLPLE 331

  Fly   279 KAHVIKCLEAELLRWRRDPKQAN----NQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVA 336
            :|||..|        .||...|.    .:|.:|.:....:.....|.||:..|||.:.::::
 Frog   332 RAHVKLC--------ARDSFVARGLPYTEKELELVAQELLFVPEEHKLFSAQGCKLVAQRIS 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	46/119 (39%)
tor3a	NP_001025592.2	P-loop containing Nucleoside Triphosphate Hydrolases	113..231	CDD:476819	46/119 (39%)