Protein Alignment Torsin and Tor2a

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001007745.2
• Gene: Tor2a / 362112
• RGDID: 1359111
• Length: 321
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 93/312 - (29%)
• Similarity: 162/312 - (51%)
• Gaps: 16/312 - (5%)

  Fly    28 LTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVR---QHIVPALK 89
            |.:....|.|....|...:...|.||....::|.    ||..|.|.|.||...:   ..::..|
  Rat    18 LVLALAAAAAWDVSFLRCSLGSFCECDFWPDLPG----LECDLARHLAGQPFGQGPGGEVIEGL- 77

  Fly    90 AHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYR 154
               .:|...::.||:|.||..||||::|:..:|..::..|.||.:|..:.....||..|....|:
  Rat    78 ---CTGPSPQQALVLSLHGWTGTGKSYVSSLLAQYLFRGGLRSPHVHHFSPIIHFPHPSHTEQYK 139

  Fly   155 VKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSH 219
            .::.:.|:..|.:|.||||:|||:||:|.|:.:.|...:..:..|.||:..||||||:|||.|..
  Rat   140 NELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLKPFLGPSWVVYGTNYRKAIFIFISNTGGEQ 204

  Fly   220 IASHLGSVMKNGRLREDTRLSDFEPLLRKAAY-NMDGGMKKTTMIESHVIDHFIPFLPMEKAHVI 283
            |........::.|.||:..|.:.||.:.:|.. |...|..::.::|..::|..:||||:::.||.
  Rat   205 INQVALEAWRSRRDREEISLQEVEPAVSQAVLDNPHHGFWRSGIMEEQLLDAVVPFLPLQRHHVR 269

  Fly   284 KCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKV 335
            .|:..||.:...:|:    :::::.:::|:..:.....||:.:||||:..::
  Rat   270 HCVLNELAQLGLEPR----EEVVQAVLDSTTYFPEEEQLFSSNGCKTVASRI 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	39/129 (30%)
		AAA	100..224	CDD:214640	48/123 (39%)
Tor2a	NP_001007745.2	AAA_22	84..175	CDD:379165	33/90 (37%)
		ClpA	<154..279	CDD:223616	46/124 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340718
Domainoid	1	1.000	104	1.000	Domainoid score	I6544
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3672
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488680at33208
OrthoFinder	1	1.000	-	-		FOG0001199
OrthoInspector	1	1.000	-	-		otm44533
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.860