Protein Alignment Torsin and Tor4a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001101286.1
• Gene: Tor4a / 311795
• RGDID: 1308019
• Length: 434
• Species: Rattus norvegicus
• Alignment Length: 336
• Identity: 81/336 - (24%)
• Similarity: 135/336 - (40%)
• Gaps: 68/336 - (20%)

  Fly    28 LTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHI 92
            |.:..||...|.|          .|..||......:|.||::|:|::.||......|:..|:.::
  Rat   120 LLVAIVGFQVLNA----------IENLDDNAQRYDLDGLEKALQRSVFGQPAAVSRIMALLRDYL 174

  Fly    93 ASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKI 157
            |:...|. ||:::.||..|.||:.|...:|............|.:|..:...|:...|.:.|.::
  Rat   175 ATHVHSH-PLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARHHCPELRPVQDCRKEL 238

  Fly   158 NNAVRDTLRSCPRS----LFIFDEVDKMPSGVFDQLTSLVD-------YNAFVDGTDNTKAIFIF 211
            ...|.|.:......    |.:.||.:.:|..:.|:|..|:.       :|          ||::.
  Rat   239 AQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHN----------AIYVL 293

  Fly   212 LSNTAGSHIASHLGSVMKN------------GRLR--EDTRLSDFEPLLRKAAYNMDGGMKKTTM 262
            ||...|..| :|.  |::|            ||.:  |...|.:.:..||:            .:
  Rat   294 LSGAGGIEI-THF--VLQNASRMLPSLRHSVGRTQTEESPALEELQTSLRE------------LL 343

  Fly   263 IESHVIDH---FIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFA 324
            ...|.:.|   .:|||.::|..|:.|...|:......|:||..:.:.|.:   |..:...|. ||
  Rat   344 AREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQAQAEHLAEQL---SYYHVAGHE-FA 404

  Fly   325 ISGCKTLEKKV 335
            |:|||.:..||
  Rat   405 ITGCKQVVAKV 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	30/123 (24%)
Tor4a	NP_001101286.1	P-loop containing Nucleoside Triphosphate Hydrolases	144..246	CDD:476819	27/102 (26%)