Protein Alignment Torsin and Tor3a

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_075630.2
• Gene: Tor3a / 30935
• MGIID: 1353652
• Length: 385
• Species: Mus musculus
• Alignment Length: 324
• Identity: 98/324 - (30%)
• Similarity: 158/324 - (48%)
• Gaps: 28/324 - (8%)

  Fly    20 LPL---QSVDPLTIGAVGAVALGAYFKEHTYCRFAECCD---DRNIPARIDELERSLERTLIGQH 78
            |||   :|:|.||          |:.     |||.:||.   |..|...:..||..|...|.|||
Mouse    77 LPLWGRRSLDVLT----------AWL-----CRFQDCCSGGGDCRISNNLTGLESDLRVRLHGQH 126

  Fly    79 IVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQAD 143
            :..:.::.|:|.::...... |.|.:||||..||||||:|..:.|.:|..|.||:.|..::....
Mouse   127 LASKLVLRAVKGYLEMPQVG-KALALSFHGWSGTGKNFLARILMDNLYRDGMRSDCVKMFISTFH 190

  Fly   144 FPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVD-YNAFVDGTDNTKA 207
            ||....|..|:.::...:::|...|.:|.|:|||.:|:..|:.:.|...:: .:....|.:..:|
Mouse   191 FPHPKYVDTYKEELQRQMQETQWRCHQSTFVFDEAEKLHPGLLELLEPYLEPRSPEARGVEAPRA 255

  Fly   208 IFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFE-PLLRKAAYNMDGGMKKTTMIESHVIDHF 271
            ||:||||..||.|...:.|::|.|..||:......| ||..:.....|.....:.:::.|:||||
Mouse   256 IFLFLSNLGGSVINEVVLSLLKAGWSREEITTQHLEVPLQAEIMEAADSSFGSSGLLKKHLIDHF 320

  Fly   272 IPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKV 335
            |||||:|..||..|:....|    .......::.:::|............||:..|||::.:::
Mouse   321 IPFLPLEYCHVRLCVRDAFL----GQDLPYTEETLDEIAKMMTYVPEEERLFSSQGCKSISQRI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	43/129 (33%)
		AAA	100..224	CDD:214640	44/124 (35%)
Tor3a	NP_075630.2	Torsin	93..222	CDD:148114	43/129 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836989
Domainoid	1	1.000	102	1.000	Domainoid score	I6803
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3732
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42470
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.850