Protein Alignment Torsin and Tor1b

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_598434.2
• Gene: Tor1b / 30934
• MGIID: 1353605
• Length: 336
• Species: Mus musculus
• Alignment Length: 318
• Identity: 110/318 - (34%)
• Similarity: 179/318 - (56%)
• Gaps: 18/318 - (5%)

  Fly    26 DPLTIG-AVGAVALGAYFKEHT--YCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPA 87
            :|:::| |:|||:....:..:|  ||||.|||.:.. |.....|:..||..|.|||:..:.|:.|
Mouse    26 EPVSVGIAIGAVSALTGYLSYTDFYCRFTECCHEER-PLNTSALKLDLEEKLFGQHLATEVILKA 89

  Fly    88 LKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSN 152
            |.. ..:...|:|||.:|.||..||||||:::.:|:.:|.||.:||:|..::....||.|.::..
Mouse    90 LTG-FRNNKNSKKPLTLSLHGWAGTGKNFISQIVAENLYPKGLKSNFVHLFVSTLHFPHEQKIKV 153

  Fly   153 YRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAG 217
            |:.::...:|..:.:|..|:|||||:||:..|:.|.:...:||...|||....:||||||||..|
Mouse   154 YQDQLQKWIRGNVSACGSSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGISYRRAIFIFLSNAGG 218

  Fly   218 SHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAY-NMDGGMKKTTMIESHVIDHFIPFLPMEKAH 281
            ..|........:.||.||:.:|.|.||:|....: |...|:..:.:|:.::||:||||||:|..|
Mouse   219 DLITKTALDFWRAGRKREEIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYKH 283

  Fly   282 VIKCLEAELLRWRRDPKQANNQKIIEDIINSSIS----YDRTHSLFAISGCKTLEKKV 335
            |..|:.||:        :|....:.||::.|...    :.:...:::..||||::.::
Mouse   284 VKMCVRAEM--------RARGAAVDEDVVTSVADEMTFFPKDEKIYSDKGCKTVQSRL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	39/119 (33%)
Tor1b	NP_598434.2	P-loop containing Nucleoside Triphosphate Hydrolases	62..176	CDD:476819	39/114 (34%)
		ClpA	<172..310	CDD:440308	55/145 (38%)