Protein Alignment Torsin and Tor2a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001356151.1
• Gene: Tor2a / 30933
• MGIID: 1353596
• Length: 322
• Species: Mus musculus
• Alignment Length: 327
• Identity: 97/327 - (29%)
• Similarity: 170/327 - (51%)
• Gaps: 25/327 - (7%)

  Fly    13 SVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQ 77
            |:|.:|.|.|.:.....:.::..          |:..|.||....::|....|..|:     .||
Mouse    13 SILGLLGLALAAAAAWDVASLRC----------TFGSFCECDFWPDLPGEGWEPVRT-----GGQ 62

  Fly    78 HIVR---QHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYL 139
            ..||   :|:.|  :...|......||||:|.||..||||::|:..:|..::..|.||.:|..:.
Mouse    63 PAVRRGSKHLPP--RRPPAEDPAPSKPLVLSLHGWTGTGKSYVSSLLAQHLFRDGLRSPHVHHFS 125

  Fly   140 GQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDN 204
            ....||..|....|:.::.:.|:..|.:|.||||:|||:||:|.|:.:.|...:..:..|.||:.
Mouse   126 PIIHFPHPSRTEQYKKELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLQPFLGPSWVVYGTNY 190

  Fly   205 TKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAY-NMDGGMKKTTMIESHVI 268
            .||||||:||..|..|........::.|.||:..|.:.||::.:|.. |...|..::.::|.|::
Mouse   191 RKAIFIFISNAGGEQINQVALEAWRSHRDREEISLQEVEPVISRAVMDNPQHGFWRSGIMEEHLL 255

  Fly   269 DHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEK 333
            |..:||||:::.||..|:..||.:...:|    ::::::.:::|:..:.....||:.:||||:..
Mouse   256 DAVVPFLPLQRHHVRHCVLNELAQLGLEP----SEEVVQAVLDSTTYFPEVEQLFSSNGCKTVAS 316

  Fly   334 KV 335
            ::
Mouse   317 RL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	38/122 (31%)
Tor2a	NP_001356151.1	P-loop containing Nucleoside Triphosphate Hydrolases	42..161	CDD:476819	40/125 (32%)