Protein Alignment Torsin and Tor2a

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001356151.1
• Gene: Tor2a / 30933
• MGIID: 1353596
• Length: 322
• Species: Mus musculus
• Alignment Length: 327
• Identity: 97/327 - (29%)
• Similarity: 170/327 - (51%)
• Gaps: 25/327 - (7%)

  Fly    13 SVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQ 77
            |:|.:|.|.|.:.....:.::..          |:..|.||....::|....|..|:     .||
Mouse    13 SILGLLGLALAAAAAWDVASLRC----------TFGSFCECDFWPDLPGEGWEPVRT-----GGQ 62

  Fly    78 HIVR---QHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYL 139
            ..||   :|:.|  :...|......||||:|.||..||||::|:..:|..::..|.||.:|..:.
Mouse    63 PAVRRGSKHLPP--RRPPAEDPAPSKPLVLSLHGWTGTGKSYVSSLLAQHLFRDGLRSPHVHHFS 125

  Fly   140 GQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDN 204
            ....||..|....|:.::.:.|:..|.:|.||||:|||:||:|.|:.:.|...:..:..|.||:.
Mouse   126 PIIHFPHPSRTEQYKKELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLQPFLGPSWVVYGTNY 190

  Fly   205 TKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAY-NMDGGMKKTTMIESHVI 268
            .||||||:||..|..|........::.|.||:..|.:.||::.:|.. |...|..::.::|.|::
Mouse   191 RKAIFIFISNAGGEQINQVALEAWRSHRDREEISLQEVEPVISRAVMDNPQHGFWRSGIMEEHLL 255

  Fly   269 DHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEK 333
            |..:||||:::.||..|:..||.:...:|    ::::::.:::|:..:.....||:.:||||:..
Mouse   256 DAVVPFLPLQRHHVRHCVLNELAQLGLEP----SEEVVQAVLDSTTYFPEVEQLFSSNGCKTVAS 316

  Fly   334 KV 335
            ::
Mouse   317 RL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	41/129 (32%)
		AAA	100..224	CDD:214640	49/123 (40%)
Tor2a	NP_001356151.1	Torsin	35..161	CDD:148114	42/142 (30%)
		ClpA	<155..294	CDD:223616	47/142 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836992
Domainoid	1	1.000	102	1.000	Domainoid score	I6803
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3732
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001199
OrthoInspector	1	1.000	-	-		otm42470
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.850