Protein Alignment Torsin and Tor3a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001009683.1
• Gene: Tor3a / 304884
• RGDID: 1310101
• Length: 395
• Species: Rattus norvegicus
• Alignment Length: 327
• Identity: 97/327 - (29%)
• Similarity: 157/327 - (48%)
• Gaps: 27/327 - (8%)

  Fly    20 LPL---QSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRN--IPARIDELERSLERTLIGQHI 79
            |||   :|:|.||               ..:|||.:||...|  |......||..|...|.|||:
  Rat    88 LPLWGRRSLDMLT---------------SWFCRFQDCCSAGNCRISNNFTGLESDLRVRLHGQHL 137

  Fly    80 VRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADF 144
            ..:.::.|:|.::...... |.|.:||||..||||||||..:.|.:|..|.||:.|..::....|
  Rat   138 ASKLVLEAVKGYLEMPQVG-KALALSFHGWSGTGKNFVARMLVDNLYRDGMRSDCVKMFISTFHF 201

  Fly   145 PKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVD-YNAFVDGTDNTKAI 208
            |....|..|:..:...:::|.|.|.:|.|:|||.:|:..|:.:.|...:: .:....|.:..:||
  Rat   202 PHPKYVDLYKEDLQRQMQETQRRCQQSTFVFDEAEKLHPGLLELLEPYLEPRSPETHGAELPRAI 266

  Fly   209 FIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFE-PLLRKAAYNMDGGMKKTTMIESHVIDHFI 272
            |:.|||..||.|...:..::|.|..||:..|...| ||..:...:.|.....:.:::.|:||.||
  Rat   267 FLLLSNLGGSVINEVVLGLLKAGWSREEITLQHLEMPLQAEIIKSADSSFGSSRLLKKHLIDLFI 331

  Fly   273 PFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAM 337
            ||||:|..||..|:....|    .......::.:::|............||:..|||::.:::.:
  Rat   332 PFLPLEYRHVRLCVRDAFL----GQDLPYTEEALDEIAKMMTYVPEEEQLFSSQGCKSISQRINL 392

  Fly   338 AI 339
            .:
  Rat   393 VL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	40/121 (33%)
Tor3a	NP_001009683.1	Torsin	113..232	CDD:399367	40/119 (34%)