Protein Alignment Torsin and Tor4a

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_666227.2
• Gene: Tor4a / 227612
• MGIID: 2442720
• Length: 426
• Species: Mus musculus
• Alignment Length: 336
• Identity: 82/336 - (24%)
• Similarity: 134/336 - (39%)
• Gaps: 69/336 - (20%)

  Fly    28 LTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHI 92
            |.:..||...|.|          .|..||......:|.||::|:|::.||......|:..|:.::
Mouse   120 LLVAIVGFQVLNA----------IENLDDNAQRYDLDGLEKALQRSVFGQPAAVGRIMALLRDYL 174

  Fly    93 ASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKI 157
            |:...|. ||:::.||..|.||:.|...:|............|.:|..:...|:...|.:.|.::
Mouse   175 ATHVHSH-PLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARYHCPEPRPVQDCRKEL 238

  Fly   158 NNAVRDTLRSCPRS----LFIFDEVDKMPSGVFDQLTSLVD-------YNAFVDGTDNTKAIFIF 211
            ...|.|.:......    |.:.||.:.:|..:.|:|..|:.       :|          ||::.
Mouse   239 AQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHN----------AIYVL 293

  Fly   212 LSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYNMDGGMKKT--------------TM 262
            ||...|..| :|.  |::|.        |...|.||.:|     |..:|              .:
Mouse   294 LSGAGGIEI-THF--VLQNA--------SRMLPPLRHSA-----GSTQTEESPAQELLTSLRELL 342

  Fly   263 IESHVIDH---FIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFA 324
            ...|.:.|   .:|||.::|..|:.|...|:......|:||..:.:.|.:   |..:...|. ||
Mouse   343 AREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQALAEHLAEQL---SYYHVAGHE-FA 403

  Fly   325 ISGCKTLEKKV 335
            |:|||.:..||
Mouse   404 ITGCKQVVAKV 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	31/130 (24%)
		AAA	100..224	CDD:214640	30/134 (22%)
Tor4a	NP_666227.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..60
		Torsin	144..246	CDD:399367	27/102 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836991
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800