Protein Alignment Torsin and Clpb

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001404197.1
• Gene: Clpb / 20480
• MGIID: 1100517
• Length: 707
• Species: Mus musculus
• Alignment Length: 328
• Identity: 85/328 - (25%)
• Similarity: 130/328 - (39%)
• Gaps: 57/328 - (17%)

  Fly    21 PLQSVD----PLTIGAVGAVALGAYFKEHTYC---RFAECCDDRNIPARIDELERSLERTLIGQH 78
            |||..:    ||.....|.|.......|..|.   |..|..:.|..|     ||:.|:..:|||.
Mouse   292 PLQRNEMGHTPLDYAREGEVMKLLKTSETKYMEKQRKREAEERRRFP-----LEQRLKEHIIGQE 351

  Fly    79 IVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQAD 143
            .....:..|::...........|||..|.|..|.||..:|:|.|..|: |.::..::.  |..::
Mouse   352 SAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKYMH-KDAKKGFIR--LDMSE 413

  Fly   144 FPKESEVSNY--------RVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVD 200
            |.:..||:.:        ..:....:...|:.||.::.:||||||....|...:..|.|.....|
Mouse   414 FQERHEVAKFIGSPPGYIGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTD 478

  Fly   201 GTDNT----KAIFIFLSNTAGSHIASHLGSV------MKNGRLRE---DTRLSD----------- 241
            |...|    .||||..||.|...||.|...:      |...|:.|   |.::||
Mouse   479 GKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQMSDKITISKNFKEN 543

  Fly   242 -FEPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKI 305
             ..|:| ||.:..|..:.:        |:..:.|||...:.:|:.:..||..|.:..||.:|..:
Mouse   544 VIRPIL-KAHFRRDEFLGR--------INEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITL 599

  Fly   306 IED 308
            :.|
Mouse   600 LWD 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	29/127 (23%)
Clpb	NP_001404197.1	ANKYR	<130..316	CDD:440430	7/23 (30%)
		ANK repeat	137..164	CDD:293786
		ANK repeat	166..197	CDD:293786
		ANK repeat	265..290	CDD:293786
		ClpA	<339..655	CDD:440308	72/276 (26%)