Protein Alignment Torsin and tor-2

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_502683.2
• Gene: tor-2 / 189606
• WormBaseID: WBGene00006598
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 102/293 - (34%)
• Similarity: 166/293 - (56%)
• Gaps: 5/293 - (1%)

  Fly    48 CRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGT 112
            |.|..||.:.:| .....|.:..:..:.|||::.:.:|.::|:| .....|:||||:||||..||
 Worm     5 CLFYTCCGETDI-FNYHALYKDFDNKIFGQHLMAESVVHSIKSH-WHNEHSQKPLVLSFHGGTGT 67

  Fly   113 GKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDE 177
            |||:|.|.|.:..|..|..|.:|..::...:||.:..:.:|::::.:.:..:.|.|.||:|||||
 Worm    68 GKNYVTEIIVNNTYRSGMHSPFVNYFVATNNFPNKKYIEDYKLELKDQLIRSARRCQRSIFIFDE 132

  Fly   178 VDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDF 242
            .||:.|.:...:...:||...|.|.|..|.|||||||.....||:......:||::|....|..|
 Worm   133 TDKLQSELIQVIKPFLDYYPAVFGVDFRKTIFIFLSNKGSKEIANIALEHHENGKIRSQLELKHF 197

  Fly   243 EPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAEL-LRWRRDPKQANNQKII 306
            |..|..:|:|.:||::.|.||.:.:|||||||||:.|.:|.:|::..| .|.|.|  .|.:.:.:
 Worm   198 ERTLMLSAFNEEGGLRNTDMISNQLIDHFIPFLPLSKFYVSQCIQVHLRKRGRHD--LAKDGEFM 260

  Fly   307 EDIINSSISYDRTHSLFAISGCKTLEKKVAMAI 339
            :.:::|...:..:..:|:.||||.:..|..:.|
 Worm   261 QRVLDSLEFFPESSKIFSSSGCKRVNAKTDLEI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	41/126 (33%)
		AAA	100..224	CDD:214640	50/123 (41%)
tor-2	NP_502683.2	Torsin	5..130	CDD:148114	41/126 (33%)
		AAA	55..179	CDD:214640	50/123 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159233
Domainoid	1	1.000	109	1.000	Domainoid score	I3983
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2348
Isobase	1	0.950	-	0	Normalized mean entropy	S4332
OMA	1	1.010	-	-		QHG49139
OrthoDB	1	1.010	-	-		D1453168at2759
OrthoFinder	1	1.000	-	-		FOG0001199
OrthoInspector	1	1.000	-	-		otm14120
orthoMCL	1	0.900	-	-		OOG6_104781
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3548
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750