Protein Alignment Torsin and tor-1

DIOPT Version :9

• Sequence 1: NP_001284866.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001369805.1
• Gene: tor-1 / 189605
• WormBaseID: WBGene00006597
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 103/293 - (35%)
• Similarity: 162/293 - (55%)
• Gaps: 9/293 - (3%)

  Fly    50 FAECCDDRNIPARID--ELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGT 112
            |..||.:.:|   .|  :|.|.|.|.:.|||:|...:|.::|:| ......:||||:||||.|||
 Worm     7 FCTCCFETDI---FDYLKLHRDLSRFIYGQHLVIDTVVRSIKSH-WHNEHPQKPLVLSFHGGPGT 67

  Fly   113 GKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDE 177
            |||:|.|.||...:..|.:|.||..::...|||....:.:|::|:...:..:...|.||:|:|||
 Worm    68 GKNYVTEIIAKNTFRSGLQSPYVKYFVATKDFPNNKHIEDYKLKLKEQLIQSADGCDRSIFVFDE 132

  Fly   178 VDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDF 242
            |||:.|.:...:...:|:...|...|..|..||||||...|.||:......:|.:.|....|..|
 Worm   133 VDKLQSELVQTIKPFLDFYPAVFEVDFRKTTFIFLSNKGSSEIANIALEHRRNLKKRSQLELKHF 197

  Fly   243 EPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAEL-LRWRRDPKQANNQKII 306
            |..|...|:|..||::.|.:|.:.:|||:|||||:.|.:|.:|::..| .|.|.|  .|.:.:.:
 Worm   198 ERTLMSHAFNEKGGLRNTELISNQLIDHYIPFLPLSKFYVSQCIQVHLRKRGRHD--LAKDGEFM 260

  Fly   307 EDIINSSISYDRTHSLFAISGCKTLEKKVAMAI 339
            :.:::|...:..:..:|:.||||.::.|..:.|
 Worm   261 QRVLDSLEFFPESSKVFSSSGCKRVDAKTELEI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	47/126 (37%)
		AAA	100..224	CDD:214640	51/123 (41%)
tor-1	NP_001369805.1	Torsin	12..130	CDD:399367	44/121 (36%)
		ClpA	<13..250	CDD:223616	89/240 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159231
Domainoid	1	1.000	109	1.000	Domainoid score	I3983
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2348
Isobase	1	0.950	-	0	Normalized mean entropy	S4332
OMA	1	1.010	-	-		QHG49139
OrthoDB	1	1.010	-	-		D1453168at2759
OrthoFinder	1	1.000	-	-		FOG0001199
OrthoInspector	1	1.000	-	-		otm14120
orthoMCL	1	0.900	-	-		OOG6_104781
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3548
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750