DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Torsin and ooc-5

DIOPT Version :9

Sequence 1:	NP_001284866.1	Gene:	Torsin / 31399	FlyBaseID:	FBgn0025615	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_495916.1	Gene:	ooc-5 / 174433	WormBaseID:	WBGene00003870	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	306	Identity:	111/306 - (36%)
Similarity:	177/306 - (57%)	Gaps:	4/306 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GAVGAVALGAYF--KEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIA 93
            |...|::.||::  |:...|...|||.:.::......|:..:...|.|||:|:..:|.::|:|..
Worm    32 GTTIAISAGAFWGLKDRLKCYLYECCHEPDVNFNYHTLDADIANLLFGQHLVKDVVVNSIKSHWY 96

  Fly    94 SGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKIN 158
            :.| .|||||:||||..|:|||:|||.||:..:..|.||.:|...:...|||.::::..|:|::.
Worm    97 NEN-PRKPLVLSFHGYTGSGKNYVAEIIANNTFRLGLRSTFVQHIVATNDFPDKNKLEEYQVELR 160

  Fly   159 NAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASH 223
            |.:..|::.|.||:|||||.||:|..:...:...:||.:.:.|.|..::|||.|||..|..||..
Worm   161 NRILTTVQKCQRSIFIFDEADKLPEQLLGAIKPFLDYYSTISGVDFRRSIFILLSNKGGGEIARI 225

  Fly   224 LGSVMKNGRLREDTRLSDFEPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEA 288
            .....::|..||..||..||..|...:||..||::.:.:|.:|:||||:||||:::.||..|:.|
Worm   226 TKEQYESGYPREQLRLEAFERELMNFSYNEKGGLQMSELISNHLIDHFVPFLPLQREHVRSCVGA 290

  Fly   289 ELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKK 334
             .||.|......:|...:|.::||...:..:...|:.||||.::.|
Worm   291 -YLRKRGRGDLVSNVDFVERVLNSLQYFPESSKAFSSSGCKRVDAK 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_001284866.1	P-loop_NTPase	48..175	CDD:304359	47/126 (37%)
Torsin	NP_001284866.1	AAA	100..224	CDD:214640	52/123 (42%)
ooc-5	NP_495916.1	Torsin	51..177	CDD:148114	47/126 (37%)
ooc-5	NP_495916.1	AAA	102..227	CDD:214640	52/124 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159232
Domainoid	1	1.000	109	1.000	Domainoid score	I3983
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2348
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49139
OrthoDB	1	1.010	-	-		D1453168at2759
OrthoFinder	1	1.000	-	-		FOG0001199
OrthoInspector	1	1.000	-	-		otm14120
orthoMCL	1	0.900	-	-		OOG6_104781
Panther	1	1.100	-	-	LDO	PTHR10760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3548
SonicParanoid	1	1.000	-	-		X455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940