Protein Alignment HLH4C and ATOH8

DIOPT Version :10

• Sequence 1: NP_001259243.1
• Gene: HLH4C / 31397
• FlyBaseID: FBgn0011277
• Length: 191
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 138
• Identity: 40/138 - (28%)
• Similarity: 60/138 - (43%)
• Gaps: 19/138 - (13%)

  Fly    63 AAQPAPPPPP----TPAPRRRT-----TPIAHLDPSELVGLSREERRRRRRATLKYRTAHA---- 114
            :|.||||.||    .|||..|.     :.|:|:..:.....|...|:|...||.......|
Human   166 SAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEIKALQQT 230

  Fly   115 ------TRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVLETPXDSAGA 173
                  .|||.||...:.:|..|||.:|.....:||||:.||::|..||..|..:.:.. .:..:
Human   231 RRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHS 295

  Fly   174 SSFATSCL 181
            :...:.|:
Human   296 NLSFSECV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH4C	NP_001259243.1	bHLH_TS_HEN1	105..165	CDD:381544	23/69 (33%)
ATOH8	XP_011531441.1	bHLH_TS_ATOH8	224..291	CDD:381427	21/66 (32%)