DRSC/TRiP Functional Genomics Resources

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Protein Alignment HLH4C and ASCL5

DIOPT Version :9

Sequence 1:NP_001259243.1 Gene:HLH4C / 31397 FlyBaseID:FBgn0011277 Length:191 Species:Drosophila melanogaster
Sequence 2:NP_001257530.1 Gene:ASCL5 / 647219 HGNCID:33169 Length:206 Species:Homo sapiens


Alignment Length:176 Identity:46/176 - (26%)
Similarity:65/176 - (36%) Gaps:55/176 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 IDKRFQARMACETAAQPAPPPPPTPAPRRRTTPIAHL------DPSELVGLSREERRRRRRATLK 108
            :|:|.....:|   .|....|||..||.....|:.::      .|:|                ..
Human    10 VDRRPLGPPSC---MQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAE----------------PP 55

  Fly   109 YRTAHA----------------------------TRERIRVEAFNVSFAELRKLLPTLPPDKKLS 145
            |..|:|                            .|||.||:..|..:|.||..||....:|:||
Human    56 YYDAYAGVFPYVPFPGAFGVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLS 120

  Fly   146 KIEILKLAICYIAYLNHVLETPXDSAGASSFATSCLFNEANFFAPP 191
            |:|.|:.||.||.||..:|.:. |  |::..|:..|.......|||
Human   121 KVETLRAAIRYIKYLQELLSSAPD--GSTPPASRGLPGTGPCPAPP 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH4CNP_001259243.1 HLH 108..165 CDD:238036 26/84 (31%)
ASCL5NP_001257530.1 HLH 89..141 CDD:197674 24/51 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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