DRSC/TRiP Functional Genomics Resources

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Protein Alignment HLH4C and Ascl1

DIOPT Version :9

Sequence 1:NP_001259243.1 Gene:HLH4C / 31397 FlyBaseID:FBgn0011277 Length:191 Species:Drosophila melanogaster
Sequence 2:NP_071779.1 Gene:Ascl1 / 64186 RGDID:71010 Length:233 Species:Rattus norvegicus


Alignment Length:137 Identity:39/137 - (28%)
Similarity:61/137 - (44%) Gaps:27/137 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 ARMACETAAQPAPPPPPTPAPRRRT---TPIAHLDPSELVGLSREERRRRRRAT------LKYR- 110
            |..|...|||.|.......||:::.   :|:|...||.....|..::.:|:|::      .|.| 
  Rat    36 AAAAAAAAAQSAQQQQQQQAPQQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRL 100

  Fly   111 -----------------TAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIA 158
                             .....|||.||:..|:.||.||:.:|....:||:||:|.|:.|:.||.
  Rat   101 NFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIR 165

  Fly   159 YLNHVLE 165
            .|..:|:
  Rat   166 ALQQLLD 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH4CNP_001259243.1 HLH 108..165 CDD:238036 23/74 (31%)
Ascl1NP_071779.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 39..95 14/55 (25%)
HLH 131..173 CDD:197674 17/42 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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