DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HLH4C and tcf21

DIOPT Version :9

Sequence 1:NP_001259243.1 Gene:HLH4C / 31397 FlyBaseID:FBgn0011277 Length:191 Species:Drosophila melanogaster
Sequence 2:NP_001032770.1 Gene:tcf21 / 558148 ZFINID:ZDB-GENE-051113-88 Length:176 Species:Danio rerio


Alignment Length:84 Identity:32/84 - (38%)
Similarity:44/84 - (52%) Gaps:8/84 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 SELVGLSREERRRRRRA--------TLKYRTAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLS 145
            ||..|..|:....||.|        ....|.|...|||.|:...:.:|:.|:..||.:|||.|||
Zfish    49 SECTGKRRKSANMRRSAPNGVAQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLS 113

  Fly   146 KIEILKLAICYIAYLNHVL 164
            |::.|:||..|||:|..:|
Zfish   114 KLDTLRLASSYIAHLRQIL 132

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH4CNP_001259243.1 HLH 108..165 CDD:238036 25/57 (44%)
tcf21NP_001032770.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..84 9/34 (26%)
HLH 77..129 CDD:278439 23/51 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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