DRSC/TRiP Functional Genomics Resources

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Protein Alignment HLH4C and LYL1

DIOPT Version :9

Sequence 1:NP_001259243.1 Gene:HLH4C / 31397 FlyBaseID:FBgn0011277 Length:191 Species:Drosophila melanogaster
Sequence 2:NP_005574.2 Gene:LYL1 / 4066 HGNCID:6734 Length:280 Species:Homo sapiens


Alignment Length:201 Identity:58/201 - (28%)
Similarity:71/201 - (35%) Gaps:87/201 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 QARMACETAAQPAPPPPPTPA------------------PR-------------------RRTTP 82
            :|.|.|  |..|||.|||.||                  ||                   ..||.
Human    17 KAEMVC--APSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMPTTE 79

  Fly    83 IAHLDP--------------------------SELVG--------LSREERRRRRRATLKYRTAH 113
            :..|.|                          |..:|        .|...:||.....|.....|
Human    80 LGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRPSHCELDLAEGH 144

  Fly   114 A-----------TRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVLETP 167
            .           :|||.|.:..|.:||||||||||.|||:||||.|:|:||:.||.:|..:|.  
Human   145 QPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLR-- 207

  Fly   168 XDSAGA 173
             |.|.|
Human   208 -DQAAA 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH4CNP_001259243.1 HLH 108..165 CDD:238036 30/67 (45%)
LYL1NP_005574.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..60 14/44 (32%)
HLH 156..208 CDD:197674 30/54 (56%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 214..280
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 86 1.000 Inparanoid score I5161
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.860

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