DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HLH4C and Ferd3l

DIOPT Version :9

Sequence 1:	NP_001259243.1	Gene:	HLH4C / 31397	FlyBaseID:	FBgn0011277	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_277057.1	Gene:	Ferd3l / 114712	MGIID:	2150010	Length:	168	Species:	Mus musculus

Alignment Length:	194	Identity:	47/194 - (24%)
Similarity:	73/194 - (37%)	Gaps:	68/194 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 MAAGPPQSISLSRYYLVDDDEMIGPNNPHLVNEDYAASTTLDIDKRFQARMACETAAQPAPPPPP 72
            |||.|...:..:....|.|..:..|.:|                      :.||.       ||.
Mouse     1 MAAYPESCLDATVLNFVADLSLASPRHP----------------------LLCEF-------PPG 36

  Fly    73 TP-----------APRRRT-----------TPIAHLDPSE-------------LVGLSREERRRR 102
            .|           .|.|.:           ..:.:.||.|             |:|    ..:|:
Mouse    37 VPFGDRTLGYREGRPGRLSQFDERYQEVEGDEVEYEDPEEEEEEGEGRGRVASLLG----RPKRK 97

  Fly   103 RRATLKYRTAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVLET 166
            |..|...|.|...|||.|:...|.:|.:||:.:||...:|:||:||.|:|||.||:::..:|::
Mouse    98 RVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQS 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HLH4C	NP_001259243.1	HLH	108..165	CDD:238036	23/56 (41%)
Ferd3l	NP_277057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..88		3/22 (14%)
		bHLH domain	104..159		23/54 (43%)
		HLH	104..156	CDD:278439	23/51 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810