Protein Alignment pon and pon

DIOPT Version :10

• Sequence 1: NP_525072.2
• Gene: pon / 31394
• FlyBaseID: FBgn0025739
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_001688550.3
• Gene: pon / 5667532
• VectorBaseID: AGAMI1_013817
• Length: 701
• Species: Anopheles gambiae
• Alignment Length: 750
• Identity: 222/750 - (29%)
• Similarity: 321/750 - (42%)
• Gaps: 181/750 - (24%)

  Fly    11 AFTETP-RKRKRETLYKNAAPPP--NPQQQ----PPEKDAQDAAVASTESCFTNAAFSSTPKKLM 68
            |..||| :||||     ||...|  |..:|    |......:..:.|  |.|.|.:|
Mosquito    17 AMMETPGKKRKR-----NAETNPFLNFTEQTFSIPSSTPIHNRQIDS--SAFENPSF-------- 66

  Fly    69 VARRRLA-KENSQPNPFPGLEVKSIADLAQKQQHQQHHQQQQQQQQKLPTNPFEVLRQPPKKKKR 132
                |:| |||........:|||||||||...:..:.:...       ..|||||:|:||||||:
Mosquito    67 ----RVANKENYNLFSDSCMEVKSIADLAGATKRPKANTPD-------TCNPFEVIRKPPKKKKK 120

  Fly   133 ----------EHACFENPGLNLELPEKQ-FNPYEVVR--------SATTPAKGFVNPALNLRGSD 178
                      |.:|||||||||...:|| .||:||.|        .|...::.|||.|||:||::
Mosquito   121 QMHPAGTAPLEESCFENPGLNLAAADKQPVNPFEVPRDGDESKRKEAEELSRCFVNSALNIRGTE 185

  Fly   179 -APASLNPFEIHRPSEAS-EAACNPSGVANPALADRDSEEQLPTSLKIGLPFTPTLGCRIDFHGM 241
             .....|||||.||.||: ||.....|:..|.||..::.........|.:||||:|..||:|..:
Mosquito   186 KGTERYNPFEIVRPKEAALEAPPGSRGLPVPELAGIENPAMEMPQYAIAVPFTPSLKHRINFQEL 250

  Fly   242 SLTQLTPSKLLAEKLVFSPVP--------------------APKRSLGAISEESSMDIGKELDRY 286
            ..:.|||.::||..:|.||.|                    ..:|||..|||||  |||::||.|
Mosquito   251 PPSALTPCQMLANMVVCSPEPTKAASGYGGDTLNRNVTVTLTKRRSLSVISEES--DIGEKLDCY 313

  Fly   287 QLELENSINEAKLRKNGVLVDRELPRNSLEVELPKNTKVSLVMETNTQELMMQEVVTVDTQVERR 351
            ||||||||||||.||.                          .:..|......     .|...||
Mosquito   314 QLELENSINEAKARKQ--------------------------RQGETTPFTFS-----GTGHRRR 347

  Fly   352 LVCTRRRTLTEISEASEVEEDTEKLLEQDREAEVILEQEKILEQEMVSERERHLTREKQLKQEKL 416
            .|   ||:|.::...|.:.:...:|.:...:...:.:..|:.|..:..|:|.....|::
Mosquito   348 SV---RRSLIDMKHISNLSQRLHELDDDQSDFTKLEDDAKVPEAAVDQEQEEEYDGEEE------ 403

  Fly   417 LEREKHLEREKLQEKLHEQLREKLQE---RAKHLEKEKLEEEELL---ERQLEEEREKEPTDGDV 475
             |.:|...:......:.::|..|:.|   ...|.|.....:....   |..:.||...:.::.||
Mosquito   404 -EEDKENRKPATPVAIGKELNSKIDETDTTETHAEVPHCNQMTFTITKETTVREEIRIDVSNPDV 467

  Fly   476 AYASESESDDEPDDLD-FKAPARFVRAYR---------------------PAALPSKAASKESLQ 518
            .:....:.:||..|:: ...||.|.||||                     ||.:..:.|..|..:
Mosquito   468 QFEEVEDFEDEEQDVELLHNPAPFQRAYRKKEPLADKPTEAIVVSDEFKHPAQIGGQVAEGEGAR 532

  Fly   519 SIGSSKSAKSAEVKPSIGMKGMIRKSIRRLMHPTS---HTTPSEVKSEDKDEHGHGQGHGQHNIL 580
            ..|       |.|| |..::.:||:|.|||: |..   |....:.:.|:|.......|.| |.::
Mosquito   533 EAG-------APVK-SHKVRDVIRRSFRRLI-PRGQAVHADEPQKEGEEKQPASQRDGEG-HGLI 587

  Fly   581 NSIRHSLRRRPQKAAE----------LEEQMEPVLA-----DVSIIDTSERTMKLRSSVAQTEYM 630
            ::||||||||....|:          :.|..:|..|     ::|||....|.:..:.|:.|  |.
Mosquito   588 STIRHSLRRRQTAKAKPTTGEEENIVVAESKQPEQAGESALEMSIIAEQPRAVFRQPSLDQ--YK 650

  Fly   631 TIEQLTNEKKHSLRNSIRRSTRDV----LRHVFHK 661
            .|....: ...:||:|:||||:|:    ::.||.|
Mosquito   651 PIAAAPS-GGGTLRSSLRRSTKDIRKQMMKSVFRK 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pon	NP_525072.2	DUF5401	<270..>443	CDD:375164	45/175 (26%)
		GBP_C	<358..445	CDD:293879	14/89 (16%)
		coiled coil	435..445	CDD:293879	3/12 (25%)
pon	XP_001688550.3	None