DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11444 and PDAP1

DIOPT Version :9

Sequence 1:	NP_001284863.1	Gene:	CG11444 / 31388	FlyBaseID:	FBgn0029715	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_055706.1	Gene:	PDAP1 / 11333	HGNCID:	14634	Length:	181	Species:	Homo sapiens

Alignment Length:	221	Identity:	96/221 - (43%)
Similarity:	121/221 - (54%)	Gaps:	65/221 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPR-GKFVNHKGRSRHFTSPEELQQESEEDSDQTSGSGSDSDDKDAAGGKASSSASKAKAPATRK 64
            ||: |:...||||:|.:|||||:.                          |...|.|.||
Human     1 MPKGGRKGGHKGRARQYTSPEEID--------------------------AQLQAEKQKA----- 34

  Fly    65 APVNRNQKSRSAAGAGAA-------SSSESESGEDSDDDSEAEARDAKKGVASLIEIENPNRV-- 120
                |.::.:...|.|||       .|.:|:..||.:||.:.:    :|||..||:|||||||
Human    35 ----REEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQK----RKGVEGLIDIENPNRVAQ 91

  Fly   121 -TKKATQKLSAIKLD-DGPAGAGGNPKPELSRREREQIEKQRARQRYEKLHAAGKTTEAKADLAR 183
             |||.||      || |||        .||||||||:||||:|::||.|:|.||||.:|||||||
Human    92 TTKKVTQ------LDLDGP--------KELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLAR 142

  Fly   184 LALIRQQREEAAAKREAEKKAADVGT 209
            ||:||:||||||.|:|.|:||.|..|
Human   143 LAIIRKQREEAARKKEEERKAKDDAT 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11444	NP_001284863.1	PP28	115..190	CDD:287254	48/78 (62%)
PDAP1	NP_055706.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..117		60/168 (36%)
		PP28	85..149	CDD:402043	47/77 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..181		11/18 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154939
Domainoid	1	1.000	96	1.000	Domainoid score	I7340
eggNOG	1	0.900	-	-		E1_KOG3375
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4548
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60099
OrthoDB	1	1.010	-	-		D1572985at2759
OrthoFinder	1	1.000	-	-		FOG0004630
OrthoInspector	1	1.000	-	-		otm40620
orthoMCL	1	0.900	-	-		OOG6_105501
Panther	1	1.100	-	-	LDO	PTHR22055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5851
SonicParanoid	1	1.000	-	-		X3831
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800