DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15912 and DPI35

DIOPT Version :9

Sequence 1:	NP_572168.1	Gene:	CG15912 / 31385	FlyBaseID:	FBgn0029712	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_013849.1	Gene:	DPI35 / 855160	SGDID:	S000004737	Length:	302	Species:	Saccharomyces cerevisiae

Alignment Length:	261	Identity:	68/261 - (26%)
Similarity:	119/261 - (45%)	Gaps:	44/261 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VANLKRFRLVTFDVTDTLLRLEDP-LRQYHQTAEEFGVTGVDRRRLEQCFRQQFKAMSSEHPNFG 71
            |..:.|..::|||..:||...:.| :.||.....::|:. .:...|...|...||.:..::|.:|
Yeast    15 VHRVARPLIITFDAYNTLYATKLPVMEQYCIVGRKYGIK-ANPSTLTNNFPHVFKKLKEDYPQYG 78

  Fly    72 RYSPGLDWQRWWLQLVARTFSCVDHGLAPEKL--EKIGQRLISVFRTSACWSHVNGAQELVQ--- 131
            :|| |:..::||..|:...|       ||.::  |.|.:.|:......:.:.:    .:|::
Yeast    79 KYS-GIKPEQWWSILIRNVF-------APNEIPDEMINEILMRFEGFDSYFVY----PDLIKFLK 131

  Fly   132 --NVRNAGKCVGIISNFDSSLPQVLDAMGFAGKFD-FILTSYEAGVMKPERGIFEIPLQ------ 187
              ..|:....:||:||.|....::|..:|....|. .|..|||..:.||:|.||:..|.
Yeast   132 DLKSRHPDVILGIVSNTDPIFYKLLKNIGLFETFSGHIYLSYELNLAKPDRAIFQYALDDIISKQ 196

  Fly   188 --------RLQIPAEQALHIGNKLDMDYEGARNCGWSGLLVSNADNPHSFASLSSLLEALKTQPI 244
                    |.:| .:...|||::|..|.|||...||:|:|:...|   .:..||:.:    ::|:
Yeast   197 PHLLEKYTREEI-LQHCFHIGDELKNDLEGAEAAGWTGILLDRND---KYGFLSNSI----SKPM 253

  Fly   245 R 245
            |
Yeast   254 R 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15912	NP_572168.1	DREG-2	15..219	CDD:274056	60/226 (27%)
CG15912	NP_572168.1	HAD-SF-IA-v1	16..214	CDD:273686	57/220 (26%)
DPI35	NP_013849.1	DREG-2	23..235	CDD:274056	60/225 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I2497
eggNOG	1	0.900	-	-		E1_COG1011
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I1588
Isobase	1	0.950	-	0	Normalized mean entropy	S2956
OMA	1	1.010	-	-		QHG55252
OrthoFinder	1	1.000	-	-		FOG0002375
OrthoInspector	1	1.000	-	-		otm46700
orthoMCL	1	0.900	-	-		OOG6_102573
Panther	1	1.100	-	-	O	PTHR46191
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1833
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.810