Protein Alignment Usf and TFE3

DIOPT Version :9

• Sequence 1: NP_572167.3
• Gene: Usf / 31384
• FlyBaseID: FBgn0029711
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: NP_006512.2
• Gene: TFE3 / 7030
• HGNCID: 11752
• Length: 575
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 83/419 - (19%)
• Similarity: 135/419 - (32%)
• Gaps: 140/419 - (33%)

  Fly    23 STSPSSVNISNANPTAGPGLMTITNHHTADLSEALV------------HSSFANGQQSLILTSDT 75
            |.:|:|..||....:||.  .|::....|.:...::            |...|..||.....|.|
Human   144 SPAPASPAISVVGVSAGG--HTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTT 206

  Fly    76 GNPLMNSQGAQIFLTICGDENSDDSQEYYTIKQEPGCDLDIHSLLPSNLQLPNNLQLPTGCEIYL 140
            ..|.:.||                     .:...||         |::.|     .||.....:.
Human   207 LGPKLASQ---------------------ALTPPPG---------PASAQ-----PLPAPEAAHT 236

  Fly   141 VKETGSLMGEPPTKAAI----KLELDTLSEKPL-------------LPSVTTSSSTQSAVITAQT 188
            ...|||....|.....|    :.|:|.:.::.:             ||..||.....|.:
Human   237 TGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTL----- 296

  Fly   189 VNPPIPGNINTTTSTTSTTTTTSVLYGSHGNGHGHGHAHAQARSQPESAGQTPSSKLEAYKKRDD 253
               |:.||:....|:....|....:..|         ..|:..:......:|.:..|...:::.|
Human   297 ---PVSGNLLDVYSSQGVATPAITVSNS---------CPAELPNIKREISETEAKALLKERQKKD 349

  Fly   254 KRRATHNEVERRRRDKINSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSSHSKGNASSS 318
                .||.:|||||..||..|.:|..::|.          |:.|....
Human   350 ----NHNLIERRRRFNINDRIKELGTLIPK----------SSDPEMRW----------------- 383

  Fly   319 SGRAPPNDSKSQILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREELDRLKRQQQLQERF 383
                    :|..||..:.:||:.:|.|....:|......||..:|::|:..:..|    :||.:.
Human   384 --------NKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQEL----ELQAQI 436

  Fly   384 H------TAGGRSTFNVTLNSLNSSATSD 406
            |      |.|        |.||.:::.||
Human   437 HGLPVPPTPG--------LLSLATTSASD 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usf	NP_572167.3	HLH	255..343	CDD:278439	19/87 (22%)
TFE3	NP_006512.2	MITF_TFEB_C_3_N	113..266	CDD:374248	31/158 (20%)
		bHLHzip_TFE3	337..427	CDD:381498	28/128 (22%)
		DUF3371	432..573	CDD:371761	10/34 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810