DRSC/TRiP Functional Genomics Resources

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Protein Alignment Usf and tfeb

DIOPT Version :9

Sequence 1:NP_572167.3 Gene:Usf / 31384 FlyBaseID:FBgn0029711 Length:437 Species:Drosophila melanogaster
Sequence 2:NP_001244121.1 Gene:tfeb / 562289 ZFINID:ZDB-GENE-090807-3 Length:493 Species:Danio rerio


Alignment Length:335 Identity:68/335 - (20%)
Similarity:112/335 - (33%) Gaps:97/335 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 LTSDTGNPLMNSQGAQIFLTICGDENSDDSQEY----YTIKQEPGCDLDIHSLL-------PSNL 124
            |.:.|...:..||..|:             :||    |..||.      :|::.       |..:
Zfish    72 LENPTDYHIRQSQRQQV-------------KEYLSTTYATKQA------VHAVTSLVQPSPPPMV 117

  Fly   125 Q-----LPNNLQLPTGCEIYLVKETGSLMGEPPTKAAIKLELDTLSEKPLLPSVTTSSSTQSAVI 184
            |     .|.|:..|......|:...|:   ..|......|.:.:..|..:...:....|.||:..
Zfish   118 QAQTGSAPPNMHSPCMRTEQLMNSAGN---SAPNSPMAMLNISSSHENEMDDLIDNIISLQSSYD 179

  Fly   185 TAQTVNPPI---PGNINTTTSTTSTTTTTSVLYGSHGNGHGHGHAHAQARSQPES-AGQTPSSKL 245
            ..|..|.|:   |..:..::|.....|         |.|.........:.|.|.: |.:...|.:
Zfish   180 DIQAYNDPVVQMPNTLPLSSSHLDVYT---------GPGMSGSAIAMTSNSCPANLAIKRELSDV 235

  Fly   246 EA-YKKRDDKRRATHNEVERRRRDKINSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSS 309
            || ...::.:::..||.:|||||..||..|.:|..|:|.                          
Zfish   236 EARAMAKERQKKDNHNLIERRRRFNINDRIKELGTMIPK-------------------------- 274

  Fly   310 HSKGNASSSSGRAPPND-----SKSQILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREE 369
                          .||     :|..||..:.:|||.||.::...|:.......:..:|:.|...
Zfish   275 --------------TNDLDVRWNKGTILRASVDYIKRMQKDVQRTREVENNFRRMEMANKQLWLR 325

  Fly   370 LDRLKRQQQL 379
            :..|:||.|:
Zfish   326 IQELERQAQI 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UsfNP_572167.3 HLH 255..343 CDD:278439 21/92 (23%)
tfebNP_001244121.1 MITF_TFEB_C_3_N 4..168 CDD:292573 21/117 (18%)
HLH 243..303 CDD:238036 23/99 (23%)
DUF3371 332..489 CDD:288684 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1318
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1708
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.840

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