Protein Alignment Usf and Mitf

DIOPT Version :9

• Sequence 1: NP_572167.3
• Gene: Usf / 31384
• FlyBaseID: FBgn0029711
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: NP_001178018.1
• Gene: Mitf / 25094
• RGDID: 3092
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 85/466 - (18%)
• Similarity: 134/466 - (28%)
• Gaps: 166/466 - (35%)

  Fly     4 HKRPRLNMEFGSSTSNTNTSTSPSSVNISNANPTAGPGLMTITNHHTADLSEALVHSSFANGQQS 68
            |:.|:...|..|....:::|...|..    :.|......||         |..|:.......|..
  Rat    18 HEEPKTYYELKSQPLKSSSSAEHSGA----SKPPLSSSTMT---------SRILLRQQLMREQMQ 69

  Fly    69 LILTSDTGNPLMNSQGAQIFLTICGDENSDDSQEYYTIKQEPGCDLDIHSLLPSNLQLP------ 127
               ..:........|.||..            |:...:.|.|..::.:.:.|||..|:|
  Rat    70 ---EQERREQQQKLQAAQFM------------QQRVAVSQTPAINVSVPTTLPSATQVPMEVLKV 119

  Fly   128 -NNLQLPTGCEI----------YLV-----KETGSLMGEP------------------PTKAAIK 158
             .:|:.||...|          ||.     |..|.::..|                  |......
  Rat   120 QTHLENPTKYHIQQAQRHQVKQYLSTTLANKHAGQVLSPPCPNQPGDHAMPPVPGSSAPNSPMAM 184

  Fly   159 LELDTLSEKPLL-------------PSVTTSSST---------QSAVITAQTVNPPIPGNINTTT 201
            |.|::..||...             |.:.|.|..         ...:....:.|..|.|.::...
  Rat   185 LTLNSNCEKEAFYKFEEQSRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPAL 249

  Fly   202 STTSTTTTTSVLYGSHGNGHGHGHAHAQARSQPESAGQTPSSKLEA----YKK------------ 250
            ...:|...:..|...:.|         |....|   |.|.|:...|    .|:
  Rat   250 QMANTLPVSGNLIDLYSN---------QGLPPP---GLTISNSCPANLPNIKRELTACIFPTESE 302

  Fly   251 -----RDDKRRATHNEVERRRRDKINSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSSH 310
                 ::.:::..||.:|||||..||..|.:|..::|.          |..|....
  Rat   303 ARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK----------SNDPDMRW--------- 348

  Fly   311 SKGNASSSSGRAPPNDSKSQILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREELDRLKR 375
                            :|..||..:.:||:.:|.|....:|.......|..:|:.|      |.|
  Rat   349 ----------------NKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHL------LLR 391

  Fly   376 QQQL--QERFH 384
            .|:|  |.|.|
  Rat   392 VQELEMQARAH 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usf	NP_572167.3	HLH	255..343	CDD:278439	19/87 (22%)
Mitf	NP_001178018.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..54		6/37 (16%)
		MITF_TFEB_C_3_N	56..194	CDD:406384	26/152 (17%)
		bHLHzip_MITF	300..403	CDD:381496	32/144 (22%)
		Leucine-zipper. /evidence=ECO:0000305	374..395		6/26 (23%)
		DUF3371	397..522	CDD:403149	3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	496..526

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810