DRSC/TRiP Functional Genomics Resources

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Protein Alignment Usf and Tfeb

DIOPT Version :9

Sequence 1:NP_572167.3 Gene:Usf / 31384 FlyBaseID:FBgn0029711 Length:437 Species:Drosophila melanogaster
Sequence 2:NP_035679.3 Gene:Tfeb / 21425 MGIID:103270 Length:534 Species:Mus musculus


Alignment Length:394 Identity:71/394 - (18%)
Similarity:120/394 - (30%) Gaps:161/394 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 EFGSSTSNTNTSTSPSSVNISNANPTAGPGLMTITNHHTADLSEALVHSSFANGQQSLILTSDTG 76
            :|.:..|....|..|:        |.|.||:.  ..|                     :|::..|
Mouse   161 KFAAHVSPAQGSPKPA--------PAASPGVR--AGH---------------------VLSTSAG 194

  Fly    77 NPLMNSQGAQIFLTICGDENSDDSQEYYTIKQEPGCDLDIHSLLPSNLQLPNNLQLPTG-CEIYL 140
            |...||..|.:.::...::..||     .|......|..:..:.| .:|:||.|.|.:. ..:| 
Mouse   195 NSAPNSPMAMLHISSNPEKEFDD-----VIDNIMRLDSVLGYINP-EMQMPNTLPLSSSHLNVY- 252

  Fly   141 VKETGSLMGEPPTKAAIKLELDTLSEKPLLPSVTTSSSTQSAVITAQTVNPPIPGNINTTTSTTS 205
                   .|:|...|:             :..||:||               .|.::......|.
Mouse   253 -------SGDPQVTAS-------------MVGVTSSS---------------CPADLTQKRELTD 282

  Fly   206 TTTTTSVLYGSHGNGHGHGHAHAQARSQPESAGQTPSSKLEAYKKRDDKRRATHNEVERRRRDKI 270
                                  |::|:..:..           :|:|:     ||.:|||||..|
Mouse   283 ----------------------AESRALAKER-----------QKKDN-----HNLIERRRRFNI 309

  Fly   271 NSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSSHSKGNASSSSGRAPPND-----SKSQ 330
            |..|.:|..::|.                                        .||     :|..
Mouse   310 NDRIKELGMLIPK----------------------------------------ANDLDVRWNKGT 334

  Fly   331 ILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREELDRLKRQQQLQERFHTAGGRSTFNVT 395
            ||..:.:||:.||.::...|:....:..|..:|:.|...:..|    ::|.|.|.....|...|.
Mouse   335 ILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQEL----EMQARVHGLPTTSPSGVN 395

  Fly   396 LNSL 399
            :..|
Mouse   396 MAEL 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UsfNP_572167.3 HLH 255..343 CDD:278439 19/92 (21%)
TfebNP_035679.3 MITF_TFEB_C_3_N 63..219 CDD:292573 17/93 (18%)
HLH 291..351 CDD:238036 23/115 (20%)
DUF3371 379..531 CDD:288684 6/21 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1318
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1708
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

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