DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3568 and CG2909

DIOPT Version :9

Sequence 1:	NP_572166.1	Gene:	CG3568 / 31383	FlyBaseID:	FBgn0029710	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_572616.1	Gene:	CG2909 / 31958	FlyBaseID:	FBgn0030189	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	255/492 - (51%)
Similarity:	334/492 - (67%)	Gaps:	12/492 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IWPGKRTNLPE-NAFTQRMLQECGQMAKPDASVD-LDNFKAISEQSPAEFGIDSCRVKAQPEDRS 86
            :||....:.|. ..|.:::|::|.|:.||....: |.|...:|.:.|.|||::|.:|..|...|.
  Fly    11 VWPAVTGDSPHLTNFGRKLLKDCRQVQKPIGGYENLGNVIKLSAEFPLEFGVNSVKVYRQSPSRL 75

  Fly    87 DRIREQIASAYPVIHERTLLLFISFLEHKLTFGSEQEKAIYKDMTVVDLVQRLLAKRCVWFFGAN 151
            .||.|::|||||:||||||.|::.:||||..:|:..||.||:::::...|||||.|||..||..|
  Fly    76 ARINEEVASAYPLIHERTLGLYLQYLEHKCRWGNAVEKPIYRNLSLCGFVQRLLVKRCASFFARN 140

  Fly   152 DYYRTMQGNIGNEGFEAVGTPAEKEPLTLTSVLSYDEIKLSALLYVSCHSEFINNGSRVNGGEVL 216
            |.|..:.|..|..|||||||..||.||.|.:|||||:|||||||.||..:||:|.|.|.|.|.|.
  Fly   141 DKYLLVSGESGASGFEAVGTREEKAPLVLANVLSYDDIKLSALLSVSSRTEFVNEGERTNCGHVD 205

  Fly   217 QNKDTIEREGVVIGLIGARFERPDVMEYQDIMITKTQNTEANGYGFDLEQISSETVTPASDLRRI 281
            .|..|:||.||::|:||||..|.::||:|||:|.:.|||...|||..|::   ...|...|.||:
  Fly   206 LNTKTLERHGVIVGMIGARLSRRNLMEFQDIVIARQQNTRERGYGMALDE---PATTRDEDYRRL 267

  Fly   282 WREFYEEPRDFIYADTPYDTTRF--EEVSQGIFDHQVMRKRYAISFDTLLLEAQDRAFKAGKPAY 344
            ||||| ..||.|:.....|..||  .:....:||:.||::|||||||.|||||:.||.:..|.||
  Fly   268 WREFY-ATRDLIHGQAVIDNQRFGPSKNKMDVFDNLVMKRRYAISFDMLLLEAEARAKRVKKLAY 331

  Fly   345 IHVVGIGLGVWKAARQQERTFLESFEGRLRALGERLSHIGVVHFSWFHLACVGSLHDGAIIPVDK 409
            |||||.||||||||.||||.|:|:||.|:|.||.||:::|:||||||.:...|.|.:|::|.:..
  Fly   332 IHVVGFGLGVWKAAEQQERIFMETFEQRMRTLGNRLNNVGLVHFSWFSITHCGGLSNGSLIEIPG 396

  Fly   410 HPQGGIRIRNSVRNPGDKLTE----DMLPVVTYAWDGNALPGNEFWANMLISTGDPAAACSTLIS 470
            ||:.|||:..|.|||..||::    .||.||:||||||||||||||..||.||||.:.|||||::
  Fly   397 HPKDGIRVLISKRNPARKLSDPEHAGMLLVVSYAWDGNALPGNEFWMKMLQSTGDSSTACSTLVA 461

  Fly   471 ELQNPHINVHYMNGANLHIASVEHGLLHVGDYARRLI 507
            ||.||:||..:.||.||||||.|||:||:.:||:|:|
  Fly   462 ELHNPYINTKFCNGGNLHIASPEHGVLHIAEYAKRVI 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3568	NP_572166.1	DUF4804	59..504	CDD:292680	242/450 (54%)
CG2909	NP_572616.1	DUF4804	48..495	CDD:292680	242/450 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452933
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28NET
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57414
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0019491
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.750