DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHOp24 and Tmed5

DIOPT Version :9

Sequence 1:	NP_001284862.1	Gene:	CHOp24 / 31382	FlyBaseID:	FBgn0029709	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_083152.1	Gene:	Tmed5 / 73130	MGIID:	1921586	Length:	229	Species:	Mus musculus

Alignment Length:	222	Identity:	62/222 - (27%)
Similarity:	107/222 - (48%)	Gaps:	30/222 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLLVGSLLILCRTSHAFIVSVD--------AHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIK 64
            ||||......|.|.:..|..|:|        |..:|||::.:.......:.::|:|||.||:|..
Mouse    11 VLLLSALPAALLRGAAGFTPSLDSDFTFTLPAGRKECFYQPMPLKASLEIEYQVLDGGELDIDFH 75

  Fly    65 ISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSI---DVGDAPQRAPGA 126
            ::.|:...:...:::|.|.:| :....|.|..||:|..|:::.|::.|.:   ::|:..|
Mouse    76 LTSPEGRTLVFEQRKSDGVHT-IETEDGDYMFCFDNTFSTISEKVIFFELILDNMGEEVQ----- 134

  Fly   127 PGEE---------EVGHTKLEDM---IRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLW 179
             |:|         :|...||||:   |..:...|:...|.|..:...:...|::.|:...||..|
Mouse   135 -GQEDWKKYITNTDVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFW 198

  Fly   180 STFEALVLVLMTVGQVYYLKRFFEVKR 206
            |....:|:|:::..|||.||..||.||
Mouse   199 SVVNLMVMVVVSAIQVYTLKSLFEDKR 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHOp24	NP_001284862.1	EMP24_GP25L	24..203	CDD:279450	52/201 (26%)
Tmed5	NP_083152.1	EMP24_GP25L	35..222	CDD:279450	49/193 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910