Protein Alignment CHOp24 and TMED2

DIOPT Version :9

• Sequence 1: NP_001284862.1
• Gene: CHOp24 / 31382
• FlyBaseID: FBgn0029709
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_001308374.1
• Gene: TMED2 / 10959
• HGNCID: 16996
• Length: 208
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 125/212 - (58%)
• Similarity: 162/212 - (76%)
• Gaps: 13/212 - (6%)

  Fly     4 TLAKVLLLVGSLLILCRTSHAFIVSVDAHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGP 68
            |||::|:|:.:||   .|...:.||:|||.||||||.|..|||.|:.|||.:|||||:|::|:||
Human     3 TLAELLVLLAALL---ATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGP 64

  Fly    69 DNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSIDVGDAPQRAPGAPGEEEVG 133
            ||..:::.::||||||||.|...|||..||:|..|:||||:|||:||:|:||:   |...|.|.|
Human    65 DNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK---GQDMETEGG 126

  Fly   134 -------HTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMT 191
                   ..|||:||.||:..:|:||||||||.||::|||::|:||||||||||.|||||||.||
Human   127 GDTWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT 191

  Fly   192 VGQVYYLKRFFEVKRVV 208
            :||:|||||||||:|||
Human   192 LGQIYYLKRFFEVRRVV 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHOp24	NP_001284862.1	EMP24_GP25L	24..203	CDD:279450	111/185 (60%)
TMED2	NP_001308374.1	EMP24_GP25L	23..203	CDD:366467	111/182 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	238	1.000	Domainoid score	I2317
eggNOG	1	0.900	-	-		E1_KOG1692
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55991
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3189
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53803
OrthoDB	1	1.010	-	-		D1328081at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	1	1.000	-	-		oto90036
orthoMCL	1	0.900	-	-		OOG6_101558
Panther	1	1.100	-	-	LDO	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R395
SonicParanoid	1	1.000	-	-		X4219
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870