DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHOp24 and TMED7-TICAM2

DIOPT Version :9

Sequence 1:	NP_001284862.1	Gene:	CHOp24 / 31382	FlyBaseID:	FBgn0029709	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_001157940.1	Gene:	TMED7-TICAM2 / 100302736	HGNCID:	33945	Length:	404	Species:	Homo sapiens

Alignment Length:	151	Identity:	54/151 - (35%)
Similarity:	81/151 - (53%)	Gaps:	4/151 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCF 98
            ::||:|::..|||..:.|:||.||..|||.::..||..|:::..|:....:||.|...|||..||
Human    46 KQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF 110

  Fly    99 NNERSSMTPKLVMFSIDVGDAPQRAPGAPGEEEVGH-TKLEDMIRELSGTLTSVKHEQEYMHVRD 162
            :||.|:.|.|.|.|...||:.|   |..|.|..|.. |::|.....:...|.||...|.:..:|:
Human   111 SNEFSTFTHKTVYFDFQVGEDP---PLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLRE 172

  Fly   163 KIHRSVNENTNSRVVLWSTFE 183
            ...||..|:.|:||..|.:.:
Human   173 AQGRSRAEDLNTRVAYWHSVD 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHOp24	NP_001284862.1	EMP24_GP25L	24..203	CDD:279450	54/151 (36%)
TMED7-TICAM2	NP_001157940.1	EMP24_GP25L	36..189	CDD:279450	53/145 (37%)
TMED7-TICAM2	NP_001157940.1	TIR_2	250..>341	CDD:304906
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1328081at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920