| Sequence 1: | NP_001162664.2 | Gene: | rb / 31381 | FlyBaseID: | FBgn0003210 | Length: | 1160 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001240781.1 | Gene: | AP4B1 / 10717 | HGNCID: | 572 | Length: | 739 | Species: | Homo sapiens |
| Alignment Length: | 565 | Identity: | 142/565 - (25%) |
|---|---|---|---|
| Similarity: | 256/565 - (45%) | Gaps: | 86/565 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 64 MKRIIGMIARGRDASDLFPAVVKNVVSKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRALKDP 128
Fly 129 NQLIRASALRVLSSIRVSMIVPIVMLAIRDSAADLSPYVRKTAAHAIPKLYSLDADQKDE--LVM 191
Fly 192 VIEKLLSDRTTLVVGSAVMAFDEVCPERVDLIHKN--YRKLCNFLLDVDEWGQVIIINMLTRYAR 254
Fly 255 TQFVDPNADDE--DLVNDGLGETPVSERFYDESSHSSSHSDDGSSDDEKNKSSTNNKNNGGGNGS 317
Fly 318 RTPSSPSNSYHIDVDHRLLLRQTKPLLQSRNASVVMAVAQLYHHVAPKNEVQLIAKALIRLLRSH 382
Fly 383 KEVQSVVLNCIASMSTKRKAIFEPHLKSFFVRTSDPTHIKLLKLDILTNLASAGSISLILREFQT 447
Fly 448 YISSSDRSFVAATIQAIGRCASSIKEVTETCLSGLVHLLSNHDEHVVAESVVVIK--RLLQTKAA 510
Fly 511 EHFEIITQ-MAKLIDYINVPAARAAIIWLIGEYNEKVPLIAPDVLRKMAKSFVDEQ-DVVKLQVL 573
Fly 574 NLGVKLYLTNP-EQTSLLCQYVFTLARYDPNYDVRDRARFLRQII 617 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| rb | NP_001162664.2 | Adaptin_N | 40..621 | CDD:279882 | 142/565 (25%) |
| HEAT repeat | 48..73 | CDD:293787 | 2/8 (25%) | ||
| HEAT repeat | 117..144 | CDD:293787 | 10/26 (38%) | ||
| Cnd1 | 129..>252 | CDD:289487 | 32/126 (25%) | ||
| HEAT repeat | 147..179 | CDD:293787 | 7/31 (23%) | ||
| HEAT repeat | 188..214 | CDD:293787 | 7/27 (26%) | ||
| AP3B1_C | 881..1019 | CDD:291462 | |||
| AP4B1 | NP_001240781.1 | Adaptin_N | 9..525 | CDD:331138 | 142/565 (25%) |
| HEAT repeat | 86..113 | CDD:293787 | 10/26 (38%) | ||
| HEAT repeat | 120..150 | CDD:293787 | 7/29 (24%) | ||
| HEAT repeat | 159..185 | CDD:293787 | 7/25 (28%) | ||
| HEAT repeat | 198..222 | CDD:293787 | 7/23 (30%) | ||
| Hinge. /evidence=ECO:0000305|PubMed:26542808 | 534..600 | ||||
| Ear, mediates interaction with TEPSIN. /evidence=ECO:0000269|PubMed:26542808 | 601..739 | ||||
| B2-adapt-app_C | 621..730 | CDD:312560 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165143300 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D323029at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.850 | |||||