DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3556 and Tcn2

DIOPT Version :9

Sequence 1:	NP_001245529.1	Gene:	CG3556 / 31380	FlyBaseID:	FBgn0029708	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_071979.2	Gene:	Tcn2 / 64365	RGDID:	620681	Length:	427	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	79/350 - (22%)
Similarity:	128/350 - (36%)	Gaps:	88/350 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 LARYVLALGSLC-------------------KDPKHFHGHDLVATLQHHE---PAQDIEFALTTL 292
            ||.|:|||.:.|                   :|.|...||       |||   .....::.|:.|
  Rat   105 LALYLLALRANCELLGSRKGDRMVSQLKWFLEDEKKAIGH-------HHEGHPHTSYYQYGLSIL 162

  Fly   293 SACSSAAHVRKRQIRRLL-----DIASGVTDQSVDAIAMVILALRCIV-----TDHRHRHLQHFV 347
            :.|.....|....:.:||     |..:.....|||..||..||..|:.     :|.|.| :...:
  Rat   163 ALCVHRKRVHDSVVGKLLYAVEHDYFTYQGHLSVDTEAMAGLAFTCLERFNFNSDLRPR-ITTAI 226

  Fly   348 RRPARGLATLQDQRGSFGSLRSTALAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPL 412
            ......:...|...|.||::.||.||:|.|........|.....|....:||            |
  Rat   227 ETVREKILKAQAPEGYFGNIYSTPLALQMLMTSPGVGLGPACLKARKSLLLS------------L 279

  Fly   413 QDG--QEPDIGVGLTADIILALGWKGLGAVRALQCD----HVIRESSDPTENGEPKLAVPFGLSS 471
            |||  |.|    .:.:.::..|..|....:.:..|.    .::..:.||....|  ::|...:||
  Rat   280 QDGAFQNP----MMISQLLPVLNHKTYLNLISPDCQAPRVMLVPATEDPVHLSE--VSVTLKVSS 338

  Fly   472 SAEESDAKNISYTYTLWVGSNVTESFSLSLVSPKNTSFFKAMTQAAEMDPRFIFEAREWPNGHYV 536
            .....:.     |.:::.|:::.:    .|...::...|...|||:             .:|.|:
  Rat   339 VLPPYER-----TVSVFAGASLED----VLKRARDLGEFTYGTQAS-------------LSGPYL 381

  Fly   537 HTLYGKKEEPRGYHYWLLYRLPELP 561
            .::.||:...|  .||.|.|:|:.|
  Rat   382 TSVLGKEAGDR--EYWQLLRVPDTP 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3556	NP_001245529.1	ISOPREN_C2_like	165..411	CDD:298658	46/192 (24%)
Tcn2	NP_071979.2	Cobalamin_bind	19..325	CDD:279466	56/243 (23%)
		Cob(II)alamin binding. /evidence=ECO:0000250	152..156		0/3 (0%)
		Cob(II)alamin binding. /evidence=ECO:0000250	193..197		1/3 (33%)
		DUF4430	353..425	CDD:291166	15/70 (21%)
		Cob(II)alamin binding. /evidence=ECO:0000250	395..397		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1233171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10559
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040