Protein Alignment CG3556 and CBLIF

DIOPT Version :9

• Sequence 1: NP_001245529.1
• Gene: CG3556 / 31380
• FlyBaseID: FBgn0029708
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_005133.2
• Gene: CBLIF / 2694
• HGNCID: 4268
• Length: 417
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 104/484 - (21%)
• Similarity: 171/484 - (35%)
• Gaps: 114/484 - (23%)

  Fly   134 SLILATPTALNGSGTPPEHQTIGQAPPTKGEQEAILRALDWLKEKRASDYGWGNDTHVVILAKEL 198
            ||:.||      :||..:.|:....|   ..||.::..:..|.|...:...:.|.:  :::|..|
Human    10 SLLWAT------AGTSTQTQSSCSVP---SAQEPLVNGIQVLMENSVTSSAYPNPS--ILIAMNL 63

  Fly   199 SGGRDPNDSVDGHVQVIQELEDTLSVKEMEIEILAMLDRHHTLPKPLDLDKLARYVLALGSLCKD 263
            :|                    ..::|..::....::...:   ..|.:.:|...::||.|.|:|
Human    64 AG--------------------AYNLKAQKLLTYQLMSSDN---NDLTIGQLGLTIMALTSSCRD 105

  Fly   264 PKHFHGHDLVATLQHH-------EP-AQDIEF---ALTTLSACSSAAH----VRKRQIRRLLDIA 313
            |     .|.|:.||..       .| |:...|   :|..|:.|...:.    :..|..:.||..:
Human   106 P-----GDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANS 165

  Fly   314 SGVTDQSVDAIAMVILALRC------IVTDHRHRHL-QHFVRRPARGLATLQDQRGSFGSLRSTA 371
            |..   :||..||..|||.|      :.::..:|.| ...::.....::......|..|.:.||.
Human   166 SPF---NVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTG 227

  Fly   372 LAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPLQDGQEPDIGVGLTADIILALGWKG 436
            ||||||..........||....:..||:..:.  |....|:.           .|.|:.:|..|.
Human   228 LAMQALSVTPEPSKKEWNCKKTTDMILNEIKQ--GKFHNPMS-----------IAQILPSLKGKT 279

  Fly   437 LGAVRALQC--DHVIRESSDPTENGEPKLAVPFGLSSSAEESDAKNISYTYTLWVGSNVTESFSL 499
            ...|..:.|  ||.::    ||....|          ....:.|.||:..||:   :|......|
Human   280 YLDVPQVTCSPDHEVQ----PTLPSNP----------GPGPTSASNITVIYTI---NNQLRGVEL 327

  Fly   500 SL-----VSPKNTS-FFKAMTQAAEMDPRFIFEAREWPNGHYVHTLYGKKEEPRGYHYWLLYRLP 558
            ..     ||.|:.| ....:.:|...:|.|.||......|..|.::....|......||...
Human   328 LFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFL--- 389

  Fly   559 ELPDPNNTPGNQLIAPVGVDELMVEDGEH 587
                ...||.|:     ||.:.:..:.||
Human   390 ----SGVTPLNE-----GVADYIPFNHEH 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3556	NP_001245529.1	ISOPREN_C2_like	165..411	CDD:298658	56/267 (21%)
CBLIF	NP_005133.2	Cobalamin_bind	24..306	CDD:307326	69/344 (20%)
		DUF4430	341..415	CDD:316952	18/81 (22%)
		Cob(II)alamin binding	365..370		1/4 (25%)
		Cob(II)alamin binding	386..395		2/15 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1233171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.040