Protein Alignment bi and tbx21

DIOPT Version :9

• Sequence 1: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: NP_001164070.1
• Gene: tbx21 / 797797
• ZFINID: ZDB-GENE-080104-3
• Length: 609
• Species: Danio rerio
• Alignment Length: 694
• Identity: 198/694 - (28%)
• Similarity: 270/694 - (38%)
• Gaps: 169/694 - (24%)

  Fly   177 NNSSSSSSNNSASAAAHPSHH-----------PTAAHHSPSTGAAAPPAGATGLPPPTPPHHLQQ 230
            |.:.:.|....|..::|...|           .|..::..|.     |.|...|   |.|.|.:.
Zfish    14 NGTDAQSFAKDAELSSHLHRHRDLSDFKMGIQDTRFYYQDSI-----PNGQESL---TLPFHAEH 70

  Fly   231 QQQQQQHPAPPPPPYFPAAALAALAGSPAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTA- 294
            .|.                     ||:..|......|.|...|.......|.:......||::|
Zfish    71 HQS---------------------AGAQTGRFYAPAPLGSCHFTSRSGTGHTYVPAGADAYSSAN 114

  Fly   295 -EDVVLASAVAHQL-------HPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVIT 351
             :||..:||..:..       ...|..|..||     |....:|.|....||.||||..|||:||
Zfish   115 GKDVYPSSADGYTASFQHGFPRAPMYSLPGLQ-----VSGKTQVLLNNYPLWAKFHKYQTEMIIT 174

  Fly   352 KSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMP-KRMYIHPDS 415
            |.||:|||.:.|.::.||..|.|.:.:|:|.||.:.:::...:|:..|||:..|| .|||:||||
Zfish   175 KQGRRMFPFLSFNITSLDPSAHYNIYVDVVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDS 239

  Fly   416 PTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRA-NDILKLPYSTFR-- 477
            |.||..||::.|||.|||||||....:......:|.|:||||||.|:|.. .|..:.|:.|.:
Zfish   240 PNTGTHWMRQEVSFGKLKLTNNKGSSNNVAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQ 304

  Fly   478 TYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVS 542
            |:||.||:|||||||||..|||||||:|||||||||       ....|.:  ..|.|:|.|:...
Zfish   305 TFVFPETQFIAVTAYQNADITQLKIDHNPFAKGFRD-------NYDTLYA--PPDPDRLTPSPTE 360

  Fly   543 SSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGP-PQSPLL---PLSHSLQQMHAHQHS 603
            |.:  |..|..      :||...|.:|         .:.| |||...   |:|.: |.......|
Zfish   361 SQQ--LLSGSC------YPHQPYLSDQ---------YMSPLPQSRFYSREPVSMT-QPCPKDPTS 407

  Fly   604 AALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGST---- 664
            :..:.|:                              |.:...|..:..|.|..|:...|.
Zfish   408 SPHSRWY------------------------------LSSQQAVPPNRLDFSAYETEYTSNSLYK 442

  Fly   665 -----GGAFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGL 724
                 .....|.|..|.......|.::|    |||..:...         .|||..|.  :||..
Zfish   443 PFPLQSSPHHPLSYYSENPFTSGAVSSA----NPGAWTASG---------RPSPQYLN--HPHHS 492

  Fly   725 YPPPHLGLLHN-PAAAAAMSPAGLNPGLLFNAQLALAAQHPALFGHAYAAAGHTPV--------- 779
            .|...|..... |:.||:.||...|.....:..|....:.|.|...:..:...|.:
Zfish   493 KPTSSLSWFRAVPSPAASSSPTATNSRFHASPSLLEPQRQPLLQDKSKESTEDTWIEAPSVKSVD 557

  Fly   780 SPLQGL------KSHRFSPYSLPGSLGSAFDAVTPGSNANRSGD 817
            |...||      |..|.|||:          :.|..|..|||.:
Zfish   558 SADSGLFEGGESKKRRVSPYT----------SSTENSPPNRSAE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	14/66 (21%)
		T-box	330..513	CDD:279278	97/186 (52%)
tbx21	NP_001164070.1	TBOX	150..343	CDD:238106	99/199 (50%)
		T-box_assoc	363..608	CDD:292794	60/302 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810