DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx20

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_001030292.1	Gene:	tbx20 / 619590	XenbaseID:	XB-GENE-487334	Length:	440	Species:	Xenopus tropicalis

Alignment Length:	424	Identity:	154/424 - (36%)
Similarity:	223/424 - (52%)	Gaps:	92/424 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 TLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADD--YRYKFHNS 393
            :||.|:||:|||.|||||:||||||:|||.::...||:||.||||:|:|||..|:  |||.:|.|
Frog    97 SLETKELWDKFHDLGTEMIITKSGRRMFPTIRVSFSGVDADAKYIVLMDIVPVDNKRYRYAYHRS 161

  Fly   394 RWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQP 458
            .|:|||||||.:|.|:|:|||||.||||.::::|||.|:|||||..|:||.:   ||||||||||
Frog   162 SWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHI---ILNSMHKYQP 223

  Fly   459 RFHLVRAND----ILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGA--- 516
            |.|:::..|    :|.|....|||::|:||.|.|||||||:.||:||||:|||||||||:..
Frog   224 RVHIIKKKDHTASLLNLKSEEFRTFIFQETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTD 288

  Fly   517 GKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVG 581
            .:||..::|:...            |.:|:|:                   ....|:    ||:|
Frog   289 IERESVESLIQKH------------SYARSPI-------------------RTYGDE----DVLG 318

  Fly   582 PPQSPLLPLSHSLQQMHAHQHSAALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADAD 646
            .....:    .|.........:.:|::|.:  :.:|....:|..:..|..:
Frog   319 EDGQTM----QSRGSAFTTSENLSLSSWVS--STSGFSGFQHPQSLTALGT-------------- 363

  Fly   647 VERDGSDSSCSESVGGSTGGAFRPTS-TGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIH 710
                 |.:|.:..:.....|...|.| .|.|     ...:|.|:.:...|.::||.::   |..|
Frog   364 -----STASLATPIPHPIQGTLPPYSRLGMP-----ITPSALASSMQGSGPTFPSFHM---PRYH 415

  Fly   711 PSPHLLPYLYPHGLYPPPHLGLLHNPAAAAAMSP 744
                   :.:..|.|.... ||.|   ::|.|:|
Frog   416 -------HYFQQGPYAAIQ-GLRH---SSAVMTP 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	114/187 (61%)
tbx20	NP_001030292.1	T-box	96..282	CDD:366363	114/187 (61%)
tbx20	NP_001030292.1	T-box	98..282		114/186 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910