DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx-43

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_001040883.1	Gene:	tbx-43 / 4363053	WormBaseID:	WBGene00044798	Length:	305	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	70/237 - (29%)
Similarity:	109/237 - (45%)	Gaps:	36/237 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 VTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSR 394
            |.|..|.||.:|.....||:|||.||.:||.::|...||.....|.:.:.:......:.||...|
Worm     5 VALMEKSLWREFDSQCNEMIITKIGRNLFPILEFAFKGLCEHLNYKIGVTMEPISYQKLKFTAGR 69

  Fly   395 W--------MVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILN 451
            |        ||       .|..:::    ..:|.:.:|:.:...||||||:............:.
Worm    70 WESLDIQEEMV-------QPNEVFL----MKSGRELLQRGLKLEKLKLTNSKDALQKSDQMIRVQ 123

  Fly   452 SMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRD--- 513
            ||.:|.|..::...:.:  ..::....:.|.||:||||||||:|.:.|||:..|.||:|||:
Worm   124 SMRQYMPVLNIYEISPV--GAHNQIGKFQFPETKFIAVTAYQSELVKQLKVQKNKFAQGFRESIK 186

  Fly   514 ---TGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGH 552
               |.:.||.     :|...|:|...:...:||.    :|||
Worm   187 SNATSSTKRP-----LSTTSSNSSPDSTLSMSSE----NLGH 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	58/190 (31%)
tbx-43	NP_001040883.1	T-box	5..183	CDD:279278	58/190 (31%)
tbx-43	NP_001040883.1	Ashwin	<170..>221	CDD:291969	19/59 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810