Protein Alignment bi and tbx1

DIOPT Version :9

• Sequence 1: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_005168668.1
• Gene: tbx1 / 368206
• ZFINID: ZDB-GENE-030805-5
• Length: 519
• Species: Danio rerio
• Alignment Length: 667
• Identity: 188/667 - (28%)
• Similarity: 259/667 - (38%)
• Gaps: 239/667 - (35%)

  Fly    33 LTQRPTDFSVSSLLTAGSNNNNSGNTNSGNNNSNSNNNTNSNTNN---------TNNLVAVSPTG 88
            |:.:...||::.|::|   .:.:|||....:.::.:.....|.:.         |..:.|:|
Zfish     7 LSPKANAFSIACLISA---RDQAGNTTFDKHATSLDKQAVQNCSRYIKMHYSTVTREMEAIS--- 65

  Fly    89 GGAQLSPQSNHSSSNTTTTSNTNNSSSNNNNNNSTHNNNNNHTNNNNNNNNNTSQKQGHHLSTTE 153
                 ||.....|......:.|.:|.|:.|...|                        :|||
Zfish    66 -----SPWLTQLSHFCDVAAFTTSSLSSLNTPGS------------------------YHLS--- 98

  Fly   154 EPPSPAGTPPPTIVGLPPIPPPNNNSSSSSSNNSASAAAHPSHHPTAAHHSPSTGAAAPPAGATG 218
              ||| |.|               .|...|......||.|      |.::|.|..|.||..|.:|
Zfish    99 --PSP-GDP---------------YSHHESQFEPCPAAQH------AYNYSGSNSAQAPAQGDSG 139

  Fly   219 LPPPTPPHHLQQQQQQQQHPAPPPPPYFPAAALAALAGSPAGPHPGLYPGGGLRFPPHHPGAHPH 283
                                          .:..:.:.|.:.|:..|
Zfish   140 ------------------------------TSNCSSSSSSSTPNKTL------------------ 156

  Fly   284 AHHLGSAYTTAEDVVLASAVAHQLHPAMRPLRALQPEDDGVVDDPKVT-----LEGKDLWEKFHK 343
                                                    |..:|||.     ||.|.||::|::
Zfish   157 ----------------------------------------VKKNPKVANINVQLEMKALWDEFNQ 181

  Fly   344 LGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADD--YRYKFHNSRWMVAGKADPEMP 406
            |||||::||:||:|||..:.::.|:|..|.|:||:|.:..||  |||.||:|.|:|||||||..|
Zfish   182 LGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFLPVDDKRYRYAFHSSSWLVAGKADPATP 246

  Fly   407 KRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRAN---DI 468
            .|::.|||||..|.|||:::|||.|||||||:.|.:|.:   ||||||:||||||:|..:   |.
Zfish   247 GRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI---ILNSMHRYQPRFHVVYVDPRKDS 308

  Fly   469 LKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTG-----AGKREKKQALMS- 527
            .|.....::|:||:||.|.|||||||.:||||||.:|||||||||..     ...|.....:||
Zfish   309 EKYAEENYKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLQIMSA 373

  Fly   528 -----NRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQSPL 587
                 |..|...:.|.|....||.......:|.|.|..|...|:       .::|       ||.
Zfish   374 FARTRNPMSSPPQQNGTEKEDSRREYDRDPSGNPLHSDPTHQLM-------SRVL-------SPA 424

  Fly   588 LPLSHSLQQMHA--------------------------HQHSAALAAWFNHLAGA---------- 616
            ||:   |..:||                          |.|.....|.:.|..||
Zfish   425 LPV---LGGLHAVPLTAGPRSPPHELRLDGHPQPPDTLHHHPYKYPATYEHYLGAKTRPSPYPSP 486

  Fly   617 ---GAGASEHAAAAAAN 630
               |.|...|.....||
Zfish   487 SIRGHGYHPHMNPTTAN 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	2/57 (4%)
		T-box	330..513	CDD:279278	106/192 (55%)
tbx1	XP_005168668.1	TBOX	165..355	CDD:238106	107/192 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840